DTNBP1 and CMYA5

Number of citations: 0 (PubMedID 14688250)
Data Source: HPRD (in vitro, in vivo, two hybrid)

		DTNBP1	CMYA5
Name		dystrobrevin binding protein 1	cardiomyopathy associated 5
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Postsynaptic Density Microtubule Cytoskeleton Membrane Sarcoplasm Axon Growth Cone Midbody Cytoplasmic Vesicle Membrane Synaptic Vesicle Membrane BLOC-1 Complex Cytoplasmic Vesicle Asymmetric Synapse Melanosome Membrane Sarcolemma Neuron Projection Neuronal Cell Body Dendritic Spine Synapse Postsynaptic Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Axon Cytoplasm	Nucleus Cytoplasm Sarcoplasmic Reticulum M Band Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	None
	Biological Process	Kidney Development Positive Regulation Of Neurotransmitter Secretion Positive Regulation Of Receptor Internalization Blood Coagulation Memory Anterograde Axonal Transport Regulation Of Signal Transduction Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Actin Cytoskeleton Organization Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Dendrite Morphogenesis Retina Development In Camera-type Eye Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Cilium Assembly Negative Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Protein Transmembrane Transport Regulation Of Synaptic Vesicle Exocytosis	None
Pathways		Golgi Associated Vesicle Biogenesis	None
Diseases		Hermansky-Pudlak syndrome (HPS)	None
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902 ) Corneal astigmatism ( 30306274 ) Femur bone mineral density x serum urate levels interaction ( 34046847 ) Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Multiple myeloma ( 27363682 ) Serum alkaline phosphatase levels ( 33547301 ) Squamous cell carcinoma ( 31174203 )	Bone mineral content ( 31790847 ) Hepatitis B surface antigen seroclearance in chronic hepatitis B infection ( 29975729 ) Obesity ( 23818313 ) Toenail selenium levels ( 25343990 )
Novel Interactors		8 novel interactors: BLOC1S3 CAP2 CSGALNACT1 DEK HDGFL1 NUP153 RNF144B TPMT	None recorded
Interacting Genes		51 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S5 BLOC1S6 BRF1 CCDC146 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DRC12 DST DTNA DTNB ELOVL7 HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 KRT75 MACF1 NBEA NDN NECAB2 NUF2 OIP5 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TNKS TRAF3IP1 TRIM2 TRIM27 TRIM9 VRK2 WASHC3 ZNF490	10 interacting genes: CAPN3 CLIP4 DTNBP1 DYSF HSPB2 IL6ST MYBPC2 OPTN PKNOX1 SNAPIN
Entrez ID		84062	202333
HPRD ID		06190	16728
Ensembl ID		ENSG00000047579	ENSG00000164309
Uniprot IDs		A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8	Q8N3K9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Establishment Of Melanosome Localization Melanosome Localization Melanosome Transport Pigment Granule Transport Pigment Granule Localization Axonal Transport Microtubule-based Movement Transport Along Microtubule BLOC-1 Complex Anterograde Synaptic Vesicle Transport Axo-dendritic Transport Cytoskeleton-dependent Intracellular Transport Microtubule-based Process Microtubule-based Transport Establishment Of Vesicle Localization Axon Cytoplasm Microvesicle Vesicle Localization Endosome To Melanosome Transport Plasma Membrane Bounded Cell Projection Organization Synaptic Vesicle Transport Intracellular Transport Melanosome Organization Cellular Localization Nuclear Envelope Pigment Granule Organization Cell Projection Organization Anterograde Axonal Transport Organelle Organization Vesicle Transport Along Microtubule Cytoskeleton Organization Cytoplasm Microtubule Binding Nuclear Membrane Vesicle Cytoskeletal Trafficking Centrosome Establishment Of Protein Localization Cytoskeleton Secretion Of Lysosomal Enzymes Protein Transmembrane Transport Regulation Of Organelle Organization Establishment Of Localization In Cell Positive Regulation Of Pigment Cell Differentiation Spindle Pole Plasma Membrane Bounded Cell Projection Assembly Neuron Projection Development Organelle Transport Along Microtubule Regulation Of Actin Nucleation Cell Projection Assembly Protein Transport	Regulation Of Neurotransmitter Secretion Anterograde Synaptic Vesicle Transport BLOC-1 Complex Synaptic Vesicle Membrane Structural Constituent Of Muscle T-tubule Sarcomere Organization Vesicle Transport Along Microtubule Synaptic Vesicle Transport Anterograde Axonal Transport Melanosome Organization Pigment Granule Organization Regulation Of Synaptic Vesicle Exocytosis Calcium-dependent Self Proteolysis Monocyte Activation Involved In Immune Response Vesicle Cytoskeletal Trafficking Positive Regulation Of Late Endosome To Lysosome Transport Axon Cytoplasm Axonal Transport Ligase Regulator Activity Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Actin Cytoskeleton Organization Response To Unfolded Protein Interleukin-27 Receptor Activity Leukemia Inhibitory Factor Receptor Activity Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Cytoplasmic Vesicle Axo-dendritic Transport Organelle Transport Along Microtubule Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Organelle Organization Actin Filament-based Process Cytoskeleton Organization Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Oncostatin-M Receptor Activity Interleukin-6 Receptor Complex Ciliary Neurotrophic Factor Receptor Complex Establishment Of Vesicle Localization Actomyosin Structure Organization Sarcolemma Somatic Muscle Development Ciliary Neurotrophic Factor Receptor Activity Leukemia Inhibitory Factor Signaling Pathway Interleukin-11 Receptor Activity Oncostatin-M-mediated Signaling Pathway Interleukin-11 Binding Vesicle Localization Regulation Of Regulated Secretory Pathway