MAD1L1 and MFAP1

  • Number of citations: 50 (PubMedID 32296183)
  • Data Source: BioGRID (two hybrid)

MAD1L1

MFAP1

Name mitotic arrest deficient 1 like 1 microfibril associated protein 1
Structure PDB 1GO4 PDB 5F5S
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
GWAS
  • Adult body size ( 32376654 )
  • Adverse response to drug ( 30420678 )
  • Age at first birth ( 34211149 )
  • Age at first sexual intercourse ( 34211149 27089180 )
  • Alcohol consumption (drinks per week) ( 30643258 )
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028 )
  • Anthropometric traits (multi-trait analysis) ( 30166351 )
  • Anxiety ( 31906708 )
  • Autism spectrum disorder or schizophrenia ( 28540026 )
  • Bipolar disorder ( 21926972 34002096 28115744 27329760 )
  • Bitter alcoholic beverage consumption ( 31046077 )
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203 )
  • Coronary artery disease ( 29212778 33020668 )
  • Dimensional psychopathology (Social) ( 29496196 )
  • Disruptive behavior disorder and attention deficit hyperactivity disorder ( 33495439 )
  • Gastroesophageal reflux disease ( 34187846 31527586 )
  • General factor of neuroticism ( 30867560 )
  • Gut microbiota relative abundance (Streptococcus) ( 33208821 )
  • Hand grip strength ( 29691431 )
  • Idiopathic pulmonary fibrosis ( 31710517 )
  • Longevity ( 20834067 )
  • Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269 )
  • Myocardial infarction ( 33532862 )
  • Number of sexual partners ( 30643258 )
  • Platelet count ( 32888494 )
  • Plateletcrit ( 32888494 )
  • Prostate cancer ( 29892016 )
  • Prostate cancer (advanced) ( 29892016 )
  • Refractive error ( 32231278 )
  • Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814 )
  • Risk-taking tendency (4-domain principal component model) ( 30643258 )
  • Rosacea symptom severity ( 29771307 )
  • Schizophrenia ( 30285260 22688191 28991256 23974872 29483656 )
  • Schizophrenia or bipolar disorder ( 24280982 )
  • Schizophrenia, schizoaffective disorder or bipolar disorder ( 24166486 )
  • Sepsis (28-day mortality) ( 32592749 )
  • Sleep duration (short sleep) ( 30846698 )
  • Smoking initiation ( 33082346 )
  • Smoking status (ever vs never smokers) ( 30643258 )
  • Superior frontal gyrus volume ( 31530798 )
  • Superior temporal gyrus volume ( 31530798 )
  • Systolic blood pressure ( 30578418 )
  • Testicular germ cell tumor ( 28604732 23666239 28604728 )
  • Vaginal microbiome composition (Shannon diversity index) ( 32723796 )
  • Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643 )
Interacting Genes 63 interacting genes: ALOX5 AMOTL2 ATG5 BIRC2 CAPN7 CCDC57 CCHCR1 CDC37 CDK18 CIMIP4 COIL CWF19L2 DRC4 FAM131C FAM90A1 FXR1 GPKOW HAUS1 HDAC1 HDAC2 KIF9 LENG1 LGALSL LMO1 LMO3 LNX1 MAD2L1 MAX MFAP1 MLX NDC80 NEBL NEK2 NINL NONO NTAQ1 PIBF1 PML PPP1R18 PSMA1 RNF8 SIN3A SIN3B SPATA18 SPATA2 SUPT5H SYT17 SYT6 TCAF1 TEX11 TPM1 TPM3 TPR TRIM29 TSC22D3 TSGA10 TSHZ3 TUBGCP4 UBC UBTF USP15 YJU2 ZSCAN32 88 interacting genes: ALKBH8 AMOTL2 AP2M1 BEND7 BICD2 CARD9 CCDC102B CCDC33 CCDC57 CDC14B CDCA7L CEP55 CEP57L1 CEP70 CEP76 COG6 CSNK2A1 DHX38 DHX8 DNTTIP1 DRC4 FAM9B FRA10AC1 FXR1 FXR2 GKAP1 GOLGA2 GOLGA6L9 GPRASP3 GRIPAP1 HMBOX1 HOMER3 HOOK2 HSF2BP HSPB1 IK KATNBL1 KIFC3 KLHL2 KRT40 L3MBTL3 LDOC1 LMNA LMNB2 LZTS1 MAD1L1 MCRS1 MID2 MIPOL1 MTUS2 NDC80 NGDN OGT OLIG3 PAX6 PHC2 PIBF1 PIH1D1 PLEKHF2 SNW1 SSX2IP STAC3 STX11 TADA2A TCP10L TEPSIN TFIP11 THAP1 TLE5 TRAF2 TRIM41 TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB1 ZBTB14 ZBTB8A ZFP1 ZFP41 ZFP64 ZNF398 ZNF41 ZNF558 ZNF620 ZNF71 ZNF76
Entrez ID 8379 4236
HPRD ID 04065 02569
Ensembl ID ENSG00000002822 ENSG00000140259
Uniprot IDs Q9Y6D9 P55081
PDB IDs 1GO4 4DZO 7B1F 7B1H 7B1J 5F5S 5O9Z 6AHD 7AAV 7ABF 7ABG 7ABI 8H6K 8Q7N 8QO9 8QPE 8QZS
GO Terms Enriched among Interactors