CALML3 and MYO10

Number of citations: 0 (PubMedID 11278607)
Data Source: HPRD (two hybrid, in vivo)

		CALML3	MYO10
Name		calmodulin like 3	myosin X
Structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Synaptic Vesicle Membrane Myelin Sheath Extracellular Exosome	Ruffle Nucleolus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Membrane Myosin Complex Lamellipodium Filopodium Filopodium Membrane Filopodium Tip Cell Projection Neuron Projection Neuronal Cell Body
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Cytoskeletal Protein Binding Spectrin Binding Protein-containing Complex Binding Actin Filament Binding Plus-end Directed Microfilament Motor Activity
	Biological Process	Detection Of Calcium Ion Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calcineurin-mediated Signaling	Signal Transduction Regulation Of Cell Shape Positive Regulation Of Cell-cell Adhesion Cytoskeleton-dependent Intracellular Transport Regulation Of Filopodium Assembly
Pathways		None	Regulation of actin dynamics for phagocytic cup formation Netrin-1 signaling FCGR3A-mediated phagocytosis
GWAS		Fasting insulin ( 34074324 )	Body mass index (change over time) in lung cancer or chronic obstructive pulmonary disease ( 28044437 ) Circulating odd-numbered chain saturated fatty acid levels (C17:0) ( 29738550 ) Major depressive disorder ( 23377640 ) Metabolite levels ( 23823483 ) Normal facial asymmetry (deformation magnitude) ( 30631343 ) Obesity-related traits ( 23251661 ) Polycystic ovary syndrome (adjusted for age and BMI) ( 34791234 ) Polycystic ovary syndrome (adjusted for age) ( 34791234 ) Response to antidepressants (symptom remission) ( 29160301 ) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010 )
Interacting Genes		9 interacting genes: BHLHE40 C11orf65 IQCB1 IQCN ISOC2 MAPK4 MFHAS1 MYO10 TERF2IP	10 interacting genes: ACTA1 APOBEC3C CALM1 CALML3 DYNLL1 EIF4ENIF1 ITGB5 PELI2 PLA2G10 RAPH1
Entrez ID		810	4651
HPRD ID		00244	03283
Ensembl ID		ENSG00000178363	ENSG00000145555
Uniprot IDs		P27482	B7Z3D4 Q9HD67
PDB IDs		1GGZ	2LW9 3AU4 3AU5 3PZD 5I0H 5I0I 5KG8
GO Terms Enriched among Interactors		None	Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Detection Of Calcium Ion Calcineurin-mediated Signaling Myelin Sheath Dynein Intermediate Chain Binding Dynein Complex Substantia Nigra Development Filopodium Cytoskeleton Sarcomere Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of High Voltage-gated Calcium Channel Activity Neural Nucleus Development Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Integrin Alphav-beta5 Complex Platelet Activating Factor Catabolic Process Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA