CALML3 and C11orf65

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		CALML3	C11orf65
Name		calmodulin like 3	chromosome 11 open reading frame 65
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Synaptic Vesicle Membrane Myelin Sheath Extracellular Exosome	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Detection Of Calcium Ion Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calcineurin-mediated Signaling	Negative Regulation Of Mitochondrial Fission Negative Regulation Of Protein Targeting To Mitochondrion
GWAS		Fasting insulin ( 34074324 )	Granulocyte count ( 27863252 ) Lymphocyte count ( 32888494 ) Mean corpuscular hemoglobin ( 27863252 29403010 ) Mean corpuscular volume ( 32888494 29403010 ) Mean platelet volume ( 32888494 ) Monocyte percentage of white cells ( 32888494 ) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269 ) Myeloid white cell count ( 27863252 ) Neutrophil count ( 27863252 32888494 ) Nonunion in individuals with fractures ( 30680360 ) Platelet count ( 27863252 ) Platelet distribution width ( 32888494 ) Red blood cell count ( 32888494 ) Sum basophil neutrophil counts ( 27863252 ) Sum neutrophil eosinophil counts ( 27863252 ) Uterine fibroids ( 31649266 30194396 ) White blood cell count ( 27863252 32888494 )
Interacting Genes		9 interacting genes: BHLHE40 C11orf65 IQCB1 IQCN ISOC2 MAPK4 MFHAS1 MYO10 TERF2IP	7 interacting genes: ATOSB CALM1 CALM2 CALM3 CALML3 DAPK1 SUMO1
Entrez ID		810	160140
HPRD ID		00244	14579
Ensembl ID		ENSG00000178363	ENSG00000166323
Uniprot IDs		P27482	Q8NCR3
PDB IDs		1GGZ	Not available
GO Terms Enriched among Interactors		None	Detection Of Calcium Ion Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Negative Regulation Of Transporter Activity Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Cation Transmembrane Transport Titin Binding Regulation Of Calcium Ion Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Voltage-gated Potassium Channel Complex Regulation Of Cardiac Muscle Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cell Communication By Electrical Coupling Regulation Of Monoatomic Cation Transmembrane Transport Protein Phosphatase Activator Activity Calyx Of Held Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Striated Muscle Contraction Negative Regulation Of Monoatomic Ion Transport Catalytic Complex Detection Of Chemical Stimulus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Response To Metal Ion Negative Regulation Of Transmembrane Transport Calcium Channel Complex Regulation Of Metal Ion Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Sequestering Of Calcium Ion Synaptic Vesicle Membrane Response To Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Monoatomic Ion Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcium-mediated Signaling Regulation Of Muscle Contraction Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Regulation Of Heart Contraction