TSEN2 and GABPB2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TSEN2	GABPB2
Name		tRNA splicing endonuclease subunit 2	GA binding protein transcription factor subunit beta 2
Structure			No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol	Nucleus
	Molecular Function	TRNA-intron Lyase Activity Nucleic Acid Binding Protein Binding Lyase Activity	Transcription Cis-regulatory Region Binding Protein Binding Identical Protein Binding
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing TRNA Processing	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		tRNA processing in the nucleus	None
Diseases		Pontocerebellar hypoplasia	None
GWAS		A body shape index ( 34021172 ) Hip circumference adjusted for BMI ( 34021172 ) Hip index ( 34021172 ) Systemic lupus erythematosus ( 28714469 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172 ) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )	Age at first sexual intercourse ( 34211149 ) Appendicular lean mass ( 33097823 ) Body mass index ( 26426971 )
Interacting Genes		7 interacting genes: CADPS CTAG2 GABPB2 RANBP10 TAX1BP1 TEPSIN TSEN54	10 interacting genes: CRK GORASP2 KDM1A LONRF1 PLCG2 RYBP SNRPB2 TSEN2 VAC14 ZDHHC17
Entrez ID		80746	126626
HPRD ID		10576	14536
Ensembl ID		ENSG00000154743	ENSG00000143458
Uniprot IDs		A0A7P0T8F8 A0A7P0T914 A0A7P0TA86 C9J7Z4 Q8NCE0	Q5SZG2 Q8TAK5
PDB IDs		7UXA 7ZRZ 8HMY 8HMZ 8ISS	Not available
GO Terms Enriched among Interactors		None	Response To Yeast