GEMIN6 and RNU2-1

Number of citations: 111 (PubMedID 23221635)
Data Source: BioGRID (unspecified method)

		GEMIN6	RNU2-1
Name		gem nuclear organelle associated protein 6	RNA, U2 small nuclear 1
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies	U2 SnRNP
	Molecular Function	RNA Binding Protein Binding	Pre-mRNA Branch Point Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	MRNA Branch Site Recognition
Pathways		snRNP Assembly SARS-CoV-2 modulates host translation machinery	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		16 interacting genes: ACOT11 DDIT4L GEMIN7 NUFIP1 RASL11B RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD2 SNRPD3 SNRPE SNRPF SNRPG STRAP TOX4	10 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 SMN1 SND1 STRAP
Entrez ID		79833	6066
HPRD ID		06110	Not available
Ensembl ID		ENSG00000152147	ENSG00000274585
Uniprot IDs		Q8WXD5	Not available
PDB IDs		1Y96 7BBL	Not available
GO Terms Enriched among Interactors		SMN-Sm Protein Complex 7-methylguanosine Cap Hypermethylation Spliceosomal SnRNP Assembly U2 SnRNP U4 SnRNP Methylosome Protein-RNA Complex Assembly Small Nuclear Ribonucleoprotein Complex U1 SnRNP U7 SnRNP U5 SnRNP U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome RNA Splicing, Via Transesterification Reactions PICln-Sm Protein Complex RNA Methylation Catalytic Step 2 Spliceosome RNA Splicing Macromolecule Methylation Protein-containing Complex Assembly MRNA Processing Precatalytic Spliceosome Protein-containing Complex Organization RNA Modification Spliceosomal Complex RNA Processing Methylation MRNA Metabolic Process Ribonucleoprotein Complex U2 SnRNP Binding Cellular Component Assembly Telomerase Holoenzyme Complex RNA Metabolic Process RNA Binding Histone Pre-mRNA DCP Binding Spliceosomal Tri-snRNP Complex Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process SMN Complex U2-type Prespliceosome Telomerase RNA Binding Protein Methylation Pre-mRNA Branch Point Binding MRNA Branch Site Recognition	SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Processing RNA Metabolic Process RNA Processing Nuclear Body Nucleic Acid Metabolic Process Protein-containing Complex Assembly RNA Splicing, Via Transesterification Reactions Protein-containing Complex Organization Nucleobase-containing Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Cytosol Nucleus RNA Binding Cytoplasm Nucleoplasm SMN-Gemin2 Complex RNAi Effector Complex Sm-like Protein Family Complex Cajal Body U2 SnRNP Binding U4atac SnRNA Binding RISC Complex Binding Dense Body U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding SnRNA Binding MiRNA Catabolic Process Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding MRNA Binding Small Nuclear Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex Assembly DNA-templated Transcription Termination