SHCBP1 and ZUP1

Number of citations: 0 (PubMedID 16189514)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		SHCBP1	ZUP1
Name		SHC binding and spindle associated 1	zinc finger containing ubiquitin peptidase 1
Structure		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Spindle Cytoskeleton Midbody	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding SH2 Domain Binding	Cysteine-type Deubiquitinase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Neural Precursor Cell Proliferation	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		6 interacting genes: AURKB CREBBP CTNNB1 PLK1 SHC1 ZUP1	9 interacting genes: ARHGAP45 CDKN2A CFTR CLN8 MMP14 PRMT5 RPS21 SHCBP1 UBC
Entrez ID		79801	221302
HPRD ID		11557	12840
Ensembl ID		ENSG00000171241	ENSG00000153975
Uniprot IDs		Q8NEM2	A0A0S2Z644 Q96AP4
PDB IDs		Not available	6EI1 6FGE
GO Terms Enriched among Interactors		Regulation Of DNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spindle Pole Condensed Chromosome, Centromeric Region Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Mitotic Cell Cycle Spindle Midzone Post-translational Protein Modification Positive Regulation Of DNA Metabolic Process Intracellular Signal Transduction Negative Regulation Of Apoptotic Process Regulation Of Chromosome Organization Spindle Microtubule Mitotic Spindle Pole Negative Regulation Of Programmed Cell Death Embryonic Digit Morphogenesis Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Cycle Cell Cycle G2/M Phase Transition Negative Regulation Of Macromolecule Biosynthetic Process Protein Destabilization Regulation Of Mitotic Sister Chromatid Separation Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Mitotic Cytokinesis Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Telomere Maintenance Negative Regulation Of Cell Cycle G2/M Phase Transition Cellular Response To UV Negative Regulation Of Metabolic Process Cellular Response To Light Stimulus Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Localization To Nucleus Histone H3K27 Acetyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic ERBB Signaling Pathway Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Glial Cell Fate Determination Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Regulation Of Apoptotic Process Kinase Binding Renal Outer Medulla Development Renal Vesicle Formation	Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Cell-matrix Adhesion Ligase Inhibitor Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Cellular Response To Genistein Negative Regulation Of GDF15-GFRAL Signaling Pathway Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Radial Spoke Head 2 Maintenance Of Ciliary Planar Beating Movement Pattern Positive Regulation Of Macrophage Apoptotic Process P53 Binding Regulation Of Cellular Localization Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Protein Metabolic Process Negative Regulation Of Protein Neddylation Ubiquitin-protein Transferase Inhibitor Activity Regulation Of B Cell Activation Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Proteolysis Senescence-associated Heterochromatin Focus Negative Regulation Of Immature T Cell Proliferation In Thymus Regulation Of Cell-matrix Adhesion Apoptotic Process Involved In Mammary Gland Involution Cytoplasm Regulation Of Signal Transduction By P53 Class Mediator Sterol Metabolic Process Cholesterol Metabolic Process Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Positive Regulation Of Monoatomic Anion Transport Somatic Motor Neuron Differentiation Glutamate Reuptake Retinal Rod Cell Apoptotic Process Response To Genistein GDF15-GFRAL Signaling Pathway Response To Hydroxyisoflavone Macropinosome Response To Odorant Histone H4R3 Methyltransferase Activity Peptidyl-arginine N-methylation Positive Regulation Of Dopamine Receptor Signaling Pathway Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Peptidyl-arginine Methylation Radial Spoke Head 1 Radial Spoke Assembly