PRR14 and SH3GL2

  • Number of citations: 0 (PubMedID 21900206)
  • Data Source: BioGRID (two hybrid)

PRR14

SH3GL2

Name proline rich 14 SH3 domain containing GRB2 like 2, endophilin A1
Structure No pdb structure PDB 1X03
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways None
GWAS
  • Cerebral cortical growth ( 29682794 )
  • Cognitive performance ( 19734545 )
  • FEV1 ( 30804560 )
  • HDL cholesterol levels in HIV infection ( 33109212 )
  • Heart failure ( 20445134 )
  • Lung function (FVC) ( 30804560 )
  • Midgestational circulating levels of PBDEs ( 28235828 )
  • Multiple sclerosis ( 19010793 )
  • Myopia ( 27182965 )
  • Nontraumatic osteonecrosis of the femoral head ( 32701715 )
  • Obesity-related traits ( 23251661 )
  • Obsessive-compulsive traits ( 33531474 )
  • Parkinson's disease ( 22451204 32201043 28892059 27182965 )
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892 )
  • Pursuit maintenance gain ( 29064472 )
  • Small cell lung carcinoma ( 28604730 )
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027 )
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993 )
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993 )
Interacting Genes 5 interacting genes: APP CBX5 CRK SH3BP4 SH3GL2 53 interacting genes: ACTG1 ADAM15 ADAM19 ADRB1 AMPH APP ARNT2 ATXN2 BIN1 CD2AP CLEC3B DACT1 DLGAP4 DNM1 DNM2 DPPA4 DPYSL4 EGFL6 EMD ERH F13A1 FBXO32 FXR1 GCH1 GSTM3 HLA-DQA1 IGHM IL6 ITCH ITSN1 LCP2 LRRK2 MAP4K3 MAST2 PAK2 PAXIP1 PDCD6IP PPP1R21 PPP6R1 PRR14 SH3GL3 SH3KBP1 SHANK3 SLC17A7 SYNJ1 TCEA2 TERF1 TIAM2 TMEM108 TYMS ZNF219 ZNF580 ZXDC
Entrez ID 78994 6456
HPRD ID 14541 05125
Ensembl ID ENSG00000156858 ENSG00000107295
Uniprot IDs Q9BWN1 Q99962
PDB IDs Not available 1X03 1X04 2D4C 2DBM
GO Terms Enriched among Interactors