TPD52 and ANXA6

Number of citations: 0 (PubMedID 15576473)
Data Source: HPRD (in vivo)

		TPD52	ANXA6
Name		tumor protein D52	annexin A6
Structure		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Mitochondrion Lysosomal Membrane Plasma Membrane Focal Adhesion Vesicle Membrane Membrane Extracellular Matrix Late Endosome Membrane Melanosome Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity	Phosphatidylserine Binding Calcium Ion Binding Protein Binding GTP Binding Calcium-dependent Phospholipid Binding Lipid Binding Ligand-gated Monoatomic Ion Channel Activity Cholesterol Binding Identical Protein Binding Calcium-dependent Protein Binding
	Biological Process	Positive Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis B Cell Differentiation Secretion	Calcium Ion Transport Regulation Of Muscle Contraction Monoatomic Ion Transmembrane Transport Negative Regulation Of Sequestering Of Calcium Ion Mitochondrial Calcium Ion Homeostasis Apoptotic Signaling Pathway
Pathways		Golgi Associated Vesicle Biogenesis	Smooth Muscle Contraction
GWAS		Allergic rhinitis ( 30013184 ) Allergy ( 27182965 ) Asthma ( 34103634 31959851 31619474 31361310 29273806 27182965 ) Asthma (adult onset) ( 31036433 ) Asthma (childhood onset) ( 31036433 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Fasting glucose ( 34059833 ) Kawasaki disease ( 33772158 ) Lapatinib-induced hepatotoxicity ( 25987243 ) Metabolite levels (HVA/MHPG ratio) ( 23319000 ) Metabolite levels (Pyroglutamine) ( 23934736 ) Rheumatoid arthritis ( 30423114 24390342 ) Self-reported allergy ( 23817569 )	Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 ) Inflammatory skin disease ( 25574825 ) Lymphocyte count ( 32888494 ) Psoriasis ( 25574825 25903422 ) Psoriatic arthritis ( 26626624 )
Interacting Genes		17 interacting genes: ANXA6 AR MAL2 MAPK3 SENP2 SH3GLB1 SOCS2 SPG21 SPOP SRPK2 STUB1 THAP4 TPD52L1 TPD52L2 TPD52L3 TTPA UBC	19 interacting genes: A2M CDC73 CEBPA CR2 ERBB2 IL16 LINC00632 LINC01554 MLH1 MTNR1B OGT PDE4B RASA1 RHOU S100A1 S100B SMURF1 SNCA TPD52
Entrez ID		7163	309
HPRD ID		04963	00231
Ensembl ID		ENSG00000076554	ENSG00000197043
Uniprot IDs		P55327	A0A0S2Z2Z6 A0A0S2Z377 P08133
PDB IDs		Not available	1M9I
GO Terms Enriched among Interactors		Cytoplasm Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ERBB Signaling Pathway Mammary Gland Alveolus Development Positive Regulation Of Macroautophagy Animal Organ Formation ERBB2 Signaling Pathway Lipid Binding Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Protein Stability Protein Modification By Small Protein Conjugation Insulin-like Growth Factor Receptor Signaling Pathway Prostate Induction Male Somatic Sex Determination Protein Modification Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Negative Regulation Of Establishment Of Blood-brain Barrier Post-translational Protein Modification Positive Regulation Of Chaperone-mediated Protein Complex Assembly Peroxynitrite Isomerase Activity Protein Localization To Vacuolar Membrane Response To Epidermal Growth Factor	Regulation Of Multicellular Organismal Process Regulation Of Immune System Process Positive Regulation Of Multicellular Organismal Process Signaling Receptor Binding Calcium-dependent Protein Binding Cellular Developmental Process Negative Regulation Of Complement Activation Signal Transduction Regulation Of Developmental Process Cellular Response To Epinephrine Stimulus S100 Protein Binding Response To Epinephrine Regulation Of Cell Morphogenesis Regulation Of Anatomical Structure Morphogenesis Regulation Of Complement Activation Leukocyte Activation Regulation Of Cell Shape Developmental Process Regulation Of Cell Activation Regulation Of Signal Transduction Cell Activation Enzyme Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Cell Surface Receptor Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Protein Homodimerization Activity Positive Regulation Of Inflammatory Response Regulation Of Programmed Cell Death Regulation Of Biological Quality Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Neuron Apoptotic Process Tau Protein Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Engulfment Of Target By Autophagosome Growth Factor Binding B Cell Activation Regulation Of Humoral Immune Response Positive Regulation Of Proteolysis Carbohydrate Homeostasis Glucose Homeostasis Response To Lipid Lymphocyte Activation Negative Regulation Of Complement Activation, Lectin Pathway