TRA and TRD

Number of citations: 0 (PubMedID 2546634)
Data Source: HPRD (in vivo)

		TRA	TRD
Name		T cell receptor alpha locus	T cell receptor delta locus
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex	None
	Molecular Function	Signaling Receptor Activity	None
	Biological Process	Adaptive Immune Response Detection Of Tumor Cell Immune System Process T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Response To Bacterium	None
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065 ) Narcolepsy ( 24204295 ) Periodontal disease-related phenotype (Socransky) ( 26962152 )	No GWAS studies recorded
Interacting Genes		16 interacting genes: CANX CD247 CD3D CD3G EDEM3 HLA-A HLA-B HLA-DRB1 HSPA5 LEF1 NCOA6 SNTA1 TMUB1 TRAT1 TRB TRD	4 interacting genes: CD3G TRA TRB TRG
Entrez ID		6955	6964
HPRD ID		01736	01731
Ensembl ID		Not available	Not available
Uniprot IDs		Not available	Not available
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Alpha-beta T Cell Receptor Complex Adaptive Immune Response T Cell Receptor Complex Lumenal Side Of Endoplasmic Reticulum Membrane Detection Of Biotic Stimulus Alpha-beta T Cell Activation T Cell Receptor Signaling Pathway Detection Of Bacterium T Cell Receptor Binding Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune Response Positive Regulation Of Immune System Process ERAD Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Gamma-delta T Cell Receptor Complex Antigen Processing And Presentation Of Endogenous Antigen TAP Binding T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response Positive Regulation Of T Cell Mediated Cytotoxicity Peptide Antigen Binding T Cell Activation Regulation Of T Cell Mediated Cytotoxicity Regulation Of Immune Response External Side Of Plasma Membrane Immune System Process Protection From Natural Killer Cell Mediated Cytotoxicity Immune Response-activating Signaling Pathway Immune Response To Tumor Cell ER To Golgi Transport Vesicle Membrane Immune Response-regulating Signaling Pathway Antigen Processing And Presentation Of Peptide Antigen MHC Class I Protein Complex Positive Regulation Of Leukocyte Mediated Cytotoxicity Activation Of Immune Response Clathrin-coated Endocytic Vesicle Membrane Regulation Of Immune System Process Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Lymphocyte Activation Protein Folding In Endoplasmic Reticulum Positive Thymic T Cell Selection Response To Endoplasmic Reticulum Stress Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Detection Of Stimulus Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Positive T Cell Selection Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation	Alpha-beta T Cell Receptor Complex Detection Of Tumor Cell T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Immune Response To Tumor Cell T Cell Mediated Cytotoxicity T Cell Receptor Complex Adaptive Immune Response Detection Of Biotic Stimulus T Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Lymphocyte Mediated Immunity Leukocyte Mediated Immunity Gamma-delta T Cell Receptor Complex Cell Killing Immune Response Detection Of Stimulus Signaling Receptor Activity Positive Thymic T Cell Selection T Cell Receptor Binding Immune Effector Process Positive T Cell Selection Thymic T Cell Selection Immune System Process Gamma-delta T Cell Activation T Cell Selection Signaling Receptor Complex Adaptor Activity Regulation Of Lymphocyte Apoptotic Process Clathrin-coated Endocytic Vesicle Membrane