SOX15 and HSFY1

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		SOX15	HSFY1
Name		SRY-box transcription factor 15	heat shock transcription factor Y-linked 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Brain Development Male Gonad Development Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Cell Differentiation Neuron Differentiation Skeletal Muscle Tissue Regeneration Negative Regulation Of Striated Muscle Tissue Development Positive Regulation Of Transcription By RNA Polymerase II Myoblast Development Trophoblast Giant Cell Differentiation Positive Regulation Of G0 To G1 Transition Positive Regulation Of Myoblast Proliferation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
GWAS		Atrial fibrillation ( 30061737 ) Brain morphology (MOSTest) ( 32665545 )	No GWAS studies recorded
Interacting Genes		6 interacting genes: BHLHE40 CFTR HNF1B HSFY1 NFIC NFIX	20 interacting genes: ATXN1 BANP BPIFA1 CCNK DTX2 GCM2 HGS HNRNPF JAK2 NFYC OTUD7B QRICH1 RBFOX1 RBM47 RBPMS SMARCB1 SOX15 SV2B TBX6 TOX2
Entrez ID		6665	86614
HPRD ID		03191	11850
Ensembl ID		ENSG00000129194	ENSG00000172468
Uniprot IDs		O60248	Q96LI6
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Sequence-specific Double-stranded DNA Binding Odontogenesis Of Dentin-containing Tooth Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Mesonephric Duct Formation Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Mesonephric Nephron Morphogenesis Ureteric Bud Elongation Pronephric Nephron Tubule Development Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Odontogenesis Animal Organ Morphogenesis Positive Regulation Of Anion Channel Activity Negative Regulation Of RNA Metabolic Process Hepatoblast Differentiation Regulation Of Pronephros Size Positive Regulation Of Monoatomic Anion Transport Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Branch Elongation Involved In Ureteric Bud Branching Mesonephric Duct Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development DNA Replication Positive Regulation Of Enamel Mineralization Anterior/posterior Pattern Specification Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Nephric Duct Formation Transepithelial Water Transport Regulation Of RNA Metabolic Process Nephric Duct Development Mesonephric Duct Development Negative Regulation Of Somatic Stem Cell Population Maintenance MRF Binding Positive Regulation Of Tooth Mineralization Inner Cell Mass Cell Differentiation Regulation Of Kidney Size Endodermal Cell Fate Specification Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity	Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Nucleus Positive Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Metabolic Process Regulation Of RNA Splicing Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Transcription By RNA Polymerase II Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Regulation Of G0 To G1 Transition Histone H3Y41 Kinase Activity Nuclear Receptor-mediated Mineralocorticoid Signaling Pathway Symbiont-induced Defense-related Programmed Cell Death Interleukin-35-mediated Signaling Pathway Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Nucleic Acid Metabolic Process DNA-templated Transcription Regulation Of Postsynapse To Nucleus Signaling Pathway Mesoderm Development Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Satellite Cell Activation Involved In Skeletal Muscle Regeneration Cyclin K-CDK13 Complex Cyclin K-CDK12 Complex Immune Response In Nasopharyngeal-associated Lymphoid Tissue Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism RNA Processing Regulation Of Protein Kinase Activity Nucleobase-containing Compound Biosynthetic Process