SKIC2 and TNRC17

Number of citations: 47 (PubMedID 15231747)
Data Source: BioGRID (two hybrid)

		SKIC2	TNRC17
Name		SKI2 subunit of superkiller complex	trinucleotide repeat containing 17
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ski Complex	None
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity 3'-5' RNA Helicase Activity	None
	Biological Process	RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay Rescue Of Stalled Ribosome	None
Pathways		Association of TriC/CCT with target proteins during biosynthesis mRNA decay by 3' to 5' exoribonuclease	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		15 interacting genes: CACNB3 CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA PRKAA2 RHOU SNRPB TNRC17 TSSK2 WDR1 WEE2-AS1 XRN1	1 interacting genes: SKIC2
Entrez ID		6499	27321
HPRD ID		02724	Not available
Ensembl ID		ENSG00000204351	Not available
Uniprot IDs		A0A1U9X8J1 A0A8V8TLC0 H7C5N0 Q15477	Not available
PDB IDs		7QDR 7QDS 7QDY 7QDZ 7QE0 9G8M 9G8N 9G8O 9G8P 9G8Q 9G8R	Not available
GO Terms Enriched among Interactors		Nuclear MRNA Surveillance Histone MRNA Catabolic Process Telomerase RNA Binding Histone MRNA Metabolic Process Nuclear RNA Surveillance RNA Surveillance Poly(A)-dependent SnoRNA 3'-end Processing Nucleolar Exosome (RNase Complex) Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Exosome (RNase Complex) Nuclear Exosome (RNase Complex) Sno(s)RNA Metabolic Process RRNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process Maturation Of 5.8S RRNA U1 SnRNP Negative Regulation Of Telomere Maintenance Via Telomerase MRNA Catabolic Process Protein Serine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity 3'-5'-RNA Exonuclease Activity Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Protein Serine/threonine Kinase Activity Regulation Of Membrane Repolarization Negative Regulation Of Telomere Maintenance Podosome Regulation Of Telomere Maintenance Via Telomerase Regulation Of Cellular Component Organization RNA Catabolic Process Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process Establishment Of Planar Polarity Of Follicular Epithelium Cellular Response To Puromycin Cellular Response To Cycloheximide Exonuclease Activity Protein Kinase Activity SnRNA Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening RRNA Metabolic Process Euchromatin Regulation Of Cell Morphogenesis Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Positive Regulation Of High Voltage-gated Calcium Channel Activity Nuclear Polyadenylation-dependent SnoRNA Catabolic Process Nuclear Polyadenylation-dependent SnRNA Catabolic Process Nuclear Polyadenylation-dependent CUT Catabolic Process [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Histone H2BS36 Kinase Activity Proline Dehydrogenase Activity	Ski Complex Nuclear-transcribed MRNA Catabolic Process, 3'-5' Exonucleolytic Nonsense-mediated Decay 3'-5' RNA Helicase Activity Rescue Of Stalled Ribosome Ribosome Disassembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translational Elongation Organelle Disassembly RNA Helicase Activity Nuclear-transcribed MRNA Catabolic Process Helicase Activity MRNA Catabolic Process