SRSF5 and OLFM2

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		SRSF5	OLFM2
Name		serine and arginine rich splicing factor 5	olfactomedin 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Speck	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Membrane AMPA Glutamate Receptor Complex Synapse
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding	Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome Liver Development MRNA Splice Site Recognition MRNA Processing RNA Splicing Response To Insulin Cellular Response To Insulin Stimulus Positive Regulation Of RNA Splicing Liver Regeneration	Signal Transduction Protein Secretion Positive Regulation Of Smooth Muscle Cell Differentiation Regulation Of Vascular Associated Smooth Muscle Cell Dedifferentiation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination	None
GWAS		Mean spheric corpuscular volume ( 32888494 ) Red blood cell count ( 32888494 )	Appendicular lean mass ( 33097823 ) Blood protein levels ( 30072576 ) Menarche (age at onset) ( 21102462 25231870 27182965 ) Sleep duration ( 30531941 )
Interacting Genes		19 interacting genes: CALM1 CCR2 CD101 DYRK1A HIPK3 MAPK14 MAPK6 OLFM2 PPARGC1A RPS6KA1 SMURF1 SNRPF SREK1 SRPK1 SRSF1 TIAM1 TMEM132D TNK2 ZRSR2	15 interacting genes: BLOC1S6 EIF1 FANCF GNB5 KRTAP1-1 KRTAP1-3 KRTAP10-3 NBAS NBPF19 NOTCH2NLA PKM ROBO2 RPS6 SRSF5 ST13
Entrez ID		6430	93145
HPRD ID		02948	10127
Ensembl ID		ENSG00000100650	ENSG00000105088
Uniprot IDs		B4DUA4 Q13243 Q86U32	K7EIS8 K7EKW2 O95897
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase Activity Kinase Activity Phosphorylation RNA Splicing MRNA Metabolic Process Nucleoplasm Protein Serine/threonine/tyrosine Kinase Activity MRNA Processing Spliceosomal Complex Assembly Protein Phosphorylation Spliceosomal Complex RNA Metabolic Process Protein-RNA Complex Assembly Nuclear Speck Nucleic Acid Metabolic Process MAP Kinase Activity Response To Dietary Excess Negative Regulation Of MRNA Metabolic Process Intracellular Signaling Cassette Protein-containing Complex Assembly Regulation Of MRNA Splicing, Via Spliceosome RNA Processing Positive Regulation Of Cell Differentiation Transferase Activity Intracellular Signal Transduction Positive Regulation Of Developmental Process Protein Tyrosine Kinase Activity U12-type Spliceosomal Complex Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Signal Transduction ATP Binding Protein-containing Complex Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Cell Surface Receptor Signaling Pathway Nucleobase-containing Compound Metabolic Process Cytoplasm Cellular Response To Cytokine Stimulus Regulation Of Cell Differentiation Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Non-membrane Spanning Protein Tyrosine Kinase Activity Histone H3T45 Kinase Activity Engulfment Of Target By Autophagosome Negative Regulation Of Eosinophil Degranulation Positive Regulation Of Astrocyte Chemotaxis T-helper 17 Cell Chemotaxis Chemokine (C-C Motif) Ligand 12 Binding	None