| Name |
ataxin 2 |
lymphocyte cytosolic protein 1 |
| Structure |
|
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
None
|
|
| Diseases |
|
None
|
| GWAS |
- Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081
)
- Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359
)
- Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359
)
- Allergic disease (asthma, hay fever or eczema) ( 29083406
)
- Allergic rhinitis ( 30013184
31361310
)
- Alopecia areata ( 25608926
)
- Apolipoprotein B levels ( 32203549
)
- Arthritis (juvenile idiopathic) ( 33106285
)
- Asthma ( 30929738
32296059
)
- Asthma (age of onset) ( 31036433
)
- Asthma (childhood onset) ( 30929738
31036433
)
- Asthma onset (childhood vs adult) ( 30929738
)
- Beta-2 microglubulin plasma levels ( 23417110
)
- Blood osmolality (transformed sodium) ( 28360221
)
- Blood pressure ( 21909110
)
- Body mass index ( 26426971
)
- Body mass index and coronary artery disease (pairwise) ( 33619380
)
- Body mass index and HDL-C (pairwise) ( 33619380
)
- Body mass index and systole blood pressure (pairwise) ( 33619380
)
- Caffeine consumption from coffee or tea ( 33287642
)
- Celiac disease ( 18311140
22057235
)
- Chronic kidney disease ( 20383146
)
- Coronary artery disease ( 29212778
)
- Crohn's disease ( 26192919
28067908
)
- Diastolic blood pressure ( 19430483
26390057
27736895
)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858
)
- Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962
)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858
)
- Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858
)
- Eosinophil count ( 27863252
32888494
)
- Eosinophil percentage of granulocytes ( 27863252
)
- Eosinophil percentage of white cells ( 27863252
32888494
)
- Estimated glomerular filtration rate ( 31015462
31152163
)
- Gastroesophageal reflux disease ( 31527586
)
- Glaucoma (primary open-angle) ( 26752265
33627673
)
- Glomerular filtration rate (cystatin C) ( 28452372
)
- Glycated hemoglobin levels ( 28898252
)
- HDL cholesterol ( 30275531
)
- Heart failure ( 31919418
)
- Hematocrit ( 19862010
)
- High light scatter reticulocyte count ( 27863252
)
- High light scatter reticulocyte percentage of red cells ( 27863252
)
- Hypertension ( 31879980
)
- Hypothyroidism ( 22493691
27182965
)
- Immature fraction of reticulocytes ( 27863252
)
- Inflammatory bowel disease ( 26192919
28067908
)
- Intraocular pressure ( 30054594
)
- Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761
)
- LDL cholesterol ( 30275531
)
- LDL cholesterol levels ( 32203549
)
- Left ventricle diastolic internal dimension ( 28394258
)
- Liver enzyme levels (alkaline phosphatase) ( 33972514
)
- Low density lipoprotein cholesterol levels ( 32154731
)
- Lymphocyte percentage of white cells ( 32888494
)
- Mean arterial pressure ( 27618448
)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Mean corpuscular hemoglobin ( 32888494
)
- Mean corpuscular volume ( 27863252
32888494
)
- Mean platelet volume ( 32888494
)
- Mean reticulocyte volume ( 32888494
)
- Mean spheric corpuscular volume ( 32888494
)
- Monocyte count ( 27863252
)
- Myeloproliferative neoplasms ( 33057200
)
- Myocardial infarction ( 30226566
33532862
)
- Neutrophil count ( 32888494
)
- Neutrophil percentage of granulocytes ( 27863252
)
- Neutrophil percentage of white cells ( 32888494
)
- Parental lifespan ( 30642433
)
- Parental longevity (combined parental age at death) ( 29227965
)
- Parental longevity (combined parental attained age, Martingale residuals) ( 29227965
)
- Parental longevity (father's age at death) ( 29227965
)
- Parental longevity (father's attained age) ( 29227965
)
- Parental longevity (mother's attained age) ( 29227965
)
- Peripheral artery disease ( 25009551
)
- Platelet count ( 24026423
27863252
29403010
32888494
33545615
)
- Platelet distribution width ( 27863252
)
- Plateletcrit ( 27863252
32888494
)
- Primary biliary cholangitis ( 26394269
)
- Primary biliary cirrhosis ( 22961000
)
- Primary sclerosing cholangitis ( 23603763
)
- Reaction time ( 29844566
)
- Red blood cell count ( 32888494
)
- Red blood cell traits ( 23222517
)
- Reticulocyte fraction of red cells ( 27863252
)
- Retinal vascular caliber ( 21060863
)
- Sarcoidosis ( 26051272
)
- Serum alkaline phosphatase levels ( 33547301
)
- Serum total protein levels ( 29403010
)
- Sjögren's syndrome ( 24097067
)
- Smoking initiation ( 33082346
)
- Smoking initiation (ever regular vs never regular) ( 30679032
)
- Smoking status (ever vs never smokers) ( 30643258
)
- Sum eosinophil basophil counts ( 27863252
)
- Systemic lupus erythematosus ( 26502338
28714469
33272962
)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858
)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962
)
- Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858
)
- Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858
)
- Thyroid peroxidase antibody levels ( 24586183
)
- Thyroid peroxidase antibody positivity ( 24586183
)
- Total cholesterol levels ( 30275531
)
- Urate levels ( 23263486
31578528
)
- Vitiligo ( 27723757
)
- White blood cell count ( 32888494
)
|
- Blood protein levels ( 30072576
)
- Femur bone mineral density x serum urate levels interaction ( 34046847
)
- L1-L4 bone mineral density x serum urate levels interaction ( 34046847
)
- Lymphocyte count ( 32888494
)
- Mean platelet volume ( 32888494
)
- Non-alcoholic fatty liver disease histology (other) ( 23213074
)
- Platelet count ( 32888494
)
- Platelet distribution width ( 32888494
)
- Systemic lupus erythematosus ( 26502338
)
|
| Interacting Genes |
23 interacting genes:
ACTN1
ACTN2
ATXN1
BAG6
BIN1
CEBPA
CHGB
GFI1B
GOLGA6L5P
IDH3B
KIFBP
LCP1
MIR128-1
MIR34B
MIR7-1
NCOA4
PABPC1
PLS3
POLR1H
RBFOX1
SH3GL2
SH3GL3
TDRD7
|
7 interacting genes:
AIF1
ATXN2
CEBPA
CNN3
GCA
PDE4B
PRKACA
|
| Entrez ID |
6311 |
3936 |
| HPRD ID |
03307
|
01082
|
| Ensembl ID |
ENSG00000204842
|
ENSG00000136167
|
| Uniprot IDs |
A0A5F9ZI57
F8VQP2
Q2M2R5
Q99700
V9GY86
|
P13796
|
| PDB IDs |
3KTR
|
2D85
5JOJ
5JOL
6VEC
|
| GO Terms Enriched among Interactors |
|
|