RPRD1B and TUBGCP4

Number of citations: 0 (PubMedID 16189514)
Data Source: HPRD (two hybrid)

		RPRD1B	TUBGCP4
Name		regulation of nuclear pre-mRNA domain containing 1B	tubulin gamma complex component 4
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Preinitiation Complex	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton Membrane Recycling Endosome
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Identical Protein Binding RNA Polymerase II C-terminal Domain Binding	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	RNA Polymerase II Promoter Clearance Positive Regulation Of Cell Population Proliferation Regulation Of Cell Cycle Process MRNA 3'-end Processing Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
GWAS		No GWAS studies recorded	Glycine levels ( 30837465 ) HDL cholesterol ( 30275531 ) Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Triglycerides ( 30275531 )
Interacting Genes		22 interacting genes: BIN3 CDCA8 DDIT4L EIF4ENIF1 HMG20A HMGB3 HOXC4 NUTF2 PFDN6 PIP4K2B PSMB1 RASSF3 SPG21 STAT3 STEEP1 TERF2 TNPO2 TUBGCP4 UBE2I VAX1 VPS37C WEE2-AS1	32 interacting genes: ADAMTSL4 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM
Entrez ID		58490	27229
HPRD ID		08513	10616
Ensembl ID		ENSG00000101413	ENSG00000137822
Uniprot IDs		Q9NQG5	Q9UGJ1
PDB IDs		4FLA 4FU3 4HFG 4NAD 4Q94 4Q96 9B9L	3RIP 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK
GO Terms Enriched among Interactors		Import Into Nucleus Protein Import Into Nucleus Nuclear Transport Nucleocytoplasmic Transport Cellular Localization Intracellular Protein Transport Establishment Of Protein Localization To Organelle Intracellular Transport Protein Localization To Nucleus Protein Localization To Organelle Membrane Organization Negative Regulation Of Cell Differentiation Nuclear Import Signal Receptor Activity Establishment Of Localization In Cell Nuclear Export Negative Regulation Of Developmental Process Astrocyte Differentiation Intracellular Protein Localization Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Recombination Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair SUMO Conjugating Enzyme Activity Actin Cortical Patch Localization Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA	Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Cytoskeleton Intermediate Filament Organization Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Identical Protein Binding Bergmann Glial Cell Differentiation Structural Constituent Of Skin Epidermis Scaffold Protein Binding Microtubule Astrocyte Development