ENOPH1 and RAB10

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		ENOPH1	RAB10
Name		enolase-phosphatase 1	RAB10, member RAS oncogene family
Structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Golgi Membrane Exocyst Cytoplasm Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Endosome Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Cell Projection Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network Secretory Vesicle
	Molecular Function	Magnesium Ion Binding Protein Binding Hydrolase Activity Acireductone Synthase Activity Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Amino Acid Biosynthetic Process Methionine Biosynthetic Process L-methionine Salvage From Methylthioadenosine	Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Protein Transport Vesicle-mediated Transport Endosomal Transport Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways		Methionine salvage pathway	Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs		2-OXOHEPTYLPHOSPHONIC ACID	None
GWAS		No GWAS studies recorded	Apolipoprotein B levels ( 32203549 ) Glycated hemoglobin levels ( 34059833 ) Immune response to smallpox vaccine (IL-6) ( 22542470 ) Mean corpuscular hemoglobin ( 27863252 32888494 ) Mean corpuscular hemoglobin concentration ( 32888494 ) Mean corpuscular volume ( 27863252 32888494 ) Metabolite levels (HVA) ( 23319000 ) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000 ) Metabolite levels (HVA/MHPG ratio) ( 23319000 ) Platelet distribution width ( 32888494 )
Interacting Genes		6 interacting genes: ERBB3 RAB10 RPS27 TMEM132D TSC22D2 ZNF280A	10 interacting genes: APP CEBPA ENOPH1 EVI5L MICAL1 MTNR1A PPBP RABIF RIMS1 SEPTIN9
Entrez ID		58478	10890
HPRD ID		17467	06692
Ensembl ID		ENSG00000145293	ENSG00000084733
Uniprot IDs		D6RA00 Q9UHY7	P61026
PDB IDs		1YNS 1ZS9	5LPN 5SZJ
GO Terms Enriched among Interactors		Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Negative Regulation Of Intralumenal Vesicle Formation GDP Binding Epidermal Growth Factor Catabolic Process Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Secretory Granule Membrane Establishment Of Protein Localization To Plasma Membrane Synaptic Vesicle Recycling Via Endosome Phagocytic Vesicle Membrane G Protein Activity Neuregulin Receptor Activity Vesicle-mediated Transport To The Plasma Membrane Lipophagy Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Negative Regulation Of Secretion ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Protein To Membrane Docking Negative Regulation Of Exosomal Secretion Regulation Of Endosome Organization Protein Localization To Plasma Membrane Alveolar Lamellar Body Insulin-responsive Compartment Schwann Cell Differentiation Phagosome Acidification Establishment Of Protein Localization To Membrane Presynaptic Endosome ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Protein Localization To Cell Periphery Secretory Vesicle Retromer Complex Binding Negative Regulation Of Motor Neuron Apoptotic Process Phagosome Maturation Endosomal Transport	None