PTGFRN and CD63

Number of citations: 0 (PubMedID 11278880)
Data Source: HPRD (in vitro, in vivo)

		PTGFRN	CD63
Name		prostaglandin F2 receptor inhibitor	CD63 molecule
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cell Surface Membrane	Extracellular Region Extracellular Space Nucleoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Multivesicular Body Plasma Membrane Cell Surface Endosome Membrane Membrane Platelet Dense Granule Membrane Late Endosome Membrane Endosome Lumen Vesicle Multivesicular Body Membrane Protein-containing Complex Azurophil Granule Membrane Melanosome Extracellular Exosome Multivesicular Body, Internal Vesicle
	Molecular Function	Protein Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Myoblast Fusion Involved In Skeletal Muscle Regeneration Lipid Droplet Organization	Positive Regulation Of Receptor Internalization Cell-matrix Adhesion Negative Regulation Of Epithelial Cell Migration Protein Transport Cell Migration Cell Differentiation Epithelial Cell Differentiation Endosome To Melanosome Transport Pigmentation Positive Regulation Of Cell Adhesion Positive Regulation Of Endocytosis Pigment Granule Maturation Pigment Cell Differentiation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		None	Platelet degranulation Neutrophil degranulation
GWAS		Blood protein levels ( 30072576 ) Erectile dysfunction and prostate cancer treatment ( 20932654 ) Gout (normal type) ( 32238385 ) Low susceptibility to hepatitis C infection ( 31206233 ) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577 ) Type 2 diabetes ( 30054458 30297969 )	Advanced age-related macular degeneration ( 26691988 ) Cardiac Troponin-T levels ( 31014085 ) Refractive error ( 32231278 )
Interacting Genes		5 interacting genes: CD151 CD63 CD81 CD82 CD9	18 interacting genes: AP4M1 CD82 CD9 F2RL1 GLP1R HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SLC22A1 SLC22A2 SRF TIMP1 TMEM80 VKORC1
Entrez ID		5738	967
HPRD ID		03124	01121
Ensembl ID		ENSG00000134247	ENSG00000135404
Uniprot IDs		Q9P2B2	P08962
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Myoblast Fusion Involved In Skeletal Muscle Regeneration Integrin Binding Cellular Response To Lipoprotein Particle Stimulus Myoblast Fusion Regulation Of Cell Migration Cell-cell Fusion Cellular Response To Low-density Lipoprotein Particle Stimulus Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Macrophage Migration Cell-cell Recognition Focal Adhesion Receptor Internalization Pigment Granule Maturation Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Cell Recognition Cell Surface Regulation Of Mononuclear Cell Migration Positive Regulation Of Endocytosis Cellular Pigment Accumulation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Cell Adhesion Extracellular Exosome Receptor-mediated Endocytosis Positive Regulation Of Transport Vesicle Cell Adhesion Cellular Pigmentation Plasma Membrane Cell Migration Multivesicular Body, Internal Vesicle Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Leukocyte Migration Paranodal Junction Assembly Platelet Dense Granule Membrane MHC Class II Protein Binding Osteoclast Fusion Cell Motility Positive Regulation Of Protein Catabolic Process In The Vacuole Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of T-helper 2 Cell Cytokine Production Tetraspanin-enriched Microdomain Endosome To Melanosome Transport Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Negative Regulation Of Platelet Aggregation	Myoblast Fusion Involved In Skeletal Muscle Regeneration Positive Regulation Of Extracellular Exosome Assembly Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Regulation Of Extracellular Exosome Assembly Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Membrane Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Skin Morphogenesis Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Positive Regulation Of Exocytosis Peptide Antigen Assembly With MHC Class II Protein Complex Positive Regulation Of Exosomal Secretion MHC Class II Protein Complex Neurotransmitter Transmembrane Transporter Activity Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Regulation Of Exosomal Secretion Regulation Of Body Fluid Levels Dopamine Transport Neurotransmitter Reuptake Xenobiotic Transmembrane Transporter Activity MHC Class II Protein Complex Binding Regulation Of Cell Migration Myoblast Fusion Monoamine Transport