PTGFRN and CD9

Number of citations: 0 (PubMedID 11278880)
Data Source: HPRD (in vivo, in vitro)

		PTGFRN	CD9
Name		prostaglandin F2 receptor inhibitor	CD9 molecule
Structure		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cell Surface Membrane	Extracellular Region Extracellular Space Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Protein-containing Complex Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding	Integrin Binding Protein Binding
	Biological Process	Myoblast Fusion Involved In Skeletal Muscle Regeneration Lipid Droplet Organization	Cell Adhesion Single Fertilization Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Nervous System Development Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Glial Cell Migration Oligodendrocyte Development Myoblast Fusion Involved In Skeletal Muscle Regeneration Cell Differentiation Platelet Activation Paranodal Junction Assembly Receptor Internalization Sperm-egg Recognition Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Platelet Aggregation Regulation Of Macrophage Migration
Pathways		None	Platelet degranulation Acrosome Reaction and Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin
Drugs		None	C31G
GWAS		Blood protein levels ( 30072576 ) Erectile dysfunction and prostate cancer treatment ( 20932654 ) Gout (normal type) ( 32238385 ) Low susceptibility to hepatitis C infection ( 31206233 ) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577 ) Type 2 diabetes ( 30054458 30297969 )	Colorectal cancer ( 24836286 ) Colorectal cancer or advanced adenoma ( 30510241 ) Mean platelet volume ( 22139419 27863252 32888494 ) Paclitaxel-induced neuropathy ( 23776197 ) Platelet count ( 22139419 26805783 )
Interacting Genes		5 interacting genes: CD151 CD63 CD81 CD82 CD9	25 interacting genes: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT ODF4 PRKCA PTGFRN SERPINH1 SLC22A1 SLC22A2 TSPAN4 VKORC1
Entrez ID		5738	928
HPRD ID		03124	00880
Ensembl ID		ENSG00000134247	ENSG00000010278
Uniprot IDs		Q9P2B2	A0A087WU13 A6NNI4 B4DK09 G8JLH6 P21926
PDB IDs		Not available	6K4J 6RLO 6RLR 6Z1V 6Z20
GO Terms Enriched among Interactors		Myoblast Fusion Involved In Skeletal Muscle Regeneration Integrin Binding Cellular Response To Lipoprotein Particle Stimulus Myoblast Fusion Regulation Of Cell Migration Cell-cell Fusion Cellular Response To Low-density Lipoprotein Particle Stimulus Syncytium Formation Syncytium Formation By Plasma Membrane Fusion Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Macrophage Migration Cell-cell Recognition Focal Adhesion Receptor Internalization Pigment Granule Maturation Macrophage Fusion Positive Regulation Of Adaptive Immune Memory Response CD4-positive, Alpha-beta T Cell Costimulation Cell Recognition Cell Surface Regulation Of Mononuclear Cell Migration Positive Regulation Of Endocytosis Cellular Pigment Accumulation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Regulation Of Cell Adhesion Extracellular Exosome Receptor-mediated Endocytosis Positive Regulation Of Transport Vesicle Cell Adhesion Cellular Pigmentation Plasma Membrane Cell Migration Multivesicular Body, Internal Vesicle Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Leukocyte Migration Paranodal Junction Assembly Platelet Dense Granule Membrane MHC Class II Protein Binding Osteoclast Fusion Cell Motility Positive Regulation Of Protein Catabolic Process In The Vacuole Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of T-helper 2 Cell Cytokine Production Tetraspanin-enriched Microdomain Endosome To Melanosome Transport Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Negative Regulation Of Platelet Aggregation	Cell Surface Integrin Binding Membrane Plasma Membrane External Side Of Plasma Membrane System Process Integrin Complex Regulation Of Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Cell Motility Positive Regulation Of Locomotion Learning Or Memory Regulation Of Locomotion Developmental Process Cognition Cell-matrix Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of Cell Communication Protein-containing Complex Binding Regulation Of Multicellular Organismal Process Regulation Of System Process Wound Healing, Spreading Of Epidermal Cells Mesodermal Cell Differentiation Integrin Alpha3-beta1 Complex Integrin Alpha5-beta1 Complex Pyrimidine Nucleoside Transmembrane Transporter Activity Vascular Process In Circulatory System Focal Adhesion Import Into Cell Regulation Of Epithelial Cell Migration Neurotransmitter Reuptake Laminin Binding Cell Adhesion Cell-substrate Adhesion Positive Regulation Of Signaling Myoblast Fusion Involved In Skeletal Muscle Regeneration Integrin Alpha2-beta1 Complex Putrescine Transmembrane Transporter Activity Virus Receptor Activity Circulatory System Process Regulation Of Biological Quality Positive Regulation Of Protein Localization To Membrane Myoblast Fusion Cell Adhesion Mediated By Integrin Positive Regulation Of Signal Transduction Receptor Complex Wound Healing, Spreading Of Cells Neurotransmitter Uptake Response To Muscle Activity