FAM20C and FAM118B

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		FAM20C	FAM118B
Name		FAM20C golgi associated secretory pathway kinase	family with sequence similarity 118 member B
Structure			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Extracellular Exosome	Nucleus Cajal Body
	Molecular Function	Nucleotide Binding Protease Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium Ion Binding Protein Binding ATP Binding Kinase Activity Transferase Activity Manganese Ion Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Binding Identical Protein Binding
	Biological Process	Skeletal System Development Protein Phosphorylation Positive Regulation Of Bone Mineralization Biomineral Tissue Development Osteoclast Maturation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Post-translational Protein Modification Positive Regulation Of Osteoblast Differentiation Regulation Of Phosphorus Metabolic Process Enamel Mineralization Odontoblast Differentiation Dentinogenesis	None
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	None
Diseases		Raine syndrome; Lethal osteosclerotic bone dysplasia	None
GWAS		Allergic rhinitis ( 25085501 ) Alzheimer's disease in APOE e4- carriers ( 25778476 )	No GWAS studies recorded
Interacting Genes		8 interacting genes: FAM118B P4HB PFDN1 SMN1 SUV39H2 TAF1D TK1 TSC22D1	29 interacting genes: BAG5 CEP126 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 MCM3AP MED31 NGEF PDCD10 PIAS2 QARS1 RAD54L2 RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746
Entrez ID		56975	79607
HPRD ID		13298	07952
Ensembl ID		ENSG00000177706	ENSG00000197798
Uniprot IDs		Q8IXL6	J3KP39 Q9BPY3
PDB IDs		5YH3	Not available
GO Terms Enriched among Interactors		Cellular Response To Decreased Oxygen Levels Procollagen-proline 4-dioxygenase Activity Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Cellular Response To Oxygen Levels Cellular Response To Hypoxia Peptidyl-proline Hydroxylation Procollagen-proline 4-dioxygenase Complex Cajal Body Identical Protein Binding DNA Synthesis Involved In Mitotic DNA Replication Thymidine Biosynthetic Process Thymidine Kinase Activity Negative Regulation Of Hematopoietic Stem Cell Proliferation RNA Polymerase Transcription Factor SL1 Complex Histone H3K9 Trimethyltransferase Activity Interleukin-23-mediated Signaling Pathway Thiol Oxidase Activity Prefoldin Complex Thymidine Metabolic Process Protein Folding Insulin Processing Interleukin-12-mediated Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process	Protein Sumoylation PML Body Organization