PRKCH and PPP1R14A

Number of citations: 0 (PubMedID 15003508)
Data Source: BioGRID (pull down)

		PRKCH	PPP1R14A
Name		protein kinase C eta	protein phosphatase 1 regulatory inhibitor subunit 14A
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Extracellular Exosome	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Enzyme Binding Protein Serine/threonine Kinase Inhibitor Activity Small GTPase Binding Translation Regulator Activity Metal Ion Binding Protein Serine Kinase Activity Protein Serine/threonine Kinase Binding	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity
	Biological Process	Regulation Of Translation Protein Phosphorylation Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Translation Cell Differentiation Positive Regulation Of Translation In Response To Stress Cellular Response To Amino Acid Starvation Negative Regulation Of Glial Cell Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Bicellular Tight Junction Assembly	Cellular Response To Xenobiotic Stimulus
Pathways		Effects of PIP2 hydrolysis G alpha (z) signalling events	RHO GTPases activate PKNs
GWAS		Asthma ( 32296059 ) Height ( 28552196 ) Obesity (early onset extreme) ( 23563609 ) Reading and spelling ( 23738518 ) Rheumatoid arthritis ( 22446963 24390342 30423114 ) Word reading ( 23738518 ) Yeast infection ( 28928442 )	Diverticular disease ( 30177863 )
Interacting Genes		12 interacting genes: BANP CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SRC ZBTB8OS	16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ
Entrez ID		5583	94274
HPRD ID		05669	16291
Ensembl ID		ENSG00000027075	ENSG00000167641
Uniprot IDs		P24723	Q96A00
PDB IDs		2FK9 3TXO 8FP1 8FP3	Not available
GO Terms Enriched among Interactors		Regulation Of Cellular Localization Regulation Of Protein Localization Cellular Response To Growth Factor Stimulus Regulation Of Establishment Of Protein Localization Response To Growth Factor Forebrain Development Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Protein Localization To Nucleus Integrin-mediated Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Transport Positive Regulation Of Multicellular Organismal Process Response To Peptide Hormone Positive Regulation Of Establishment Of Protein Localization T Cell Costimulation Regulation Of Protein Localization To Nucleus Cellular Response To Hormone Stimulus Ephrin Receptor Signaling Pathway Negative Regulation Of Neutrophil Activation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Multicellular Organismal Development Regulation Of Leukocyte Cell-cell Adhesion Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Phospholipase Activator Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Peptide Hormone Receptor Binding Regulation Of Neutrophil Activation Positive Regulation Of Protein Localization BMP Receptor Binding Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Neutrophil Activation Involved In Immune Response Cellular Response To Steroid Hormone Stimulus Regulation Of Cell Adhesion Regulation Of Striated Muscle Cell Differentiation Protein Kinase Activity Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Intracellular Transport Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Response To Chemical Stress Negative Regulation Of Cell Cycle Process Cellular Response To Oxygen-containing Compound Positive Regulation Of Leukocyte Cell-cell Adhesion Cell Differentiation Regulation Of Developmental Process Leukocyte Activation Tau-protein Kinase Activity Stimulatory C-type Lectin Receptor Signaling Pathway	Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase Activity Kinase Activity Protein Phosphorylation Phosphorylation Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling ATP Binding Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Signal Transduction Nucleotide Binding Transferase Activity Regulation Of Signal Transduction Signal Transduction Protein Modification Process Regulation Of Canonical Wnt Signaling Pathway Phosphate-containing Compound Metabolic Process Regulation Of Wnt Signaling Pathway Protein Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Intracellular Signal Transduction Wnt Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Catabolic Process Regulation Of Protein Localization Cytoplasm Regulation Of Proteolysis Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Localization Endocytosis Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Golgi Organization Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Cytosol Negative Regulation Of Apoptotic Process Plasma Membrane Negative Regulation Of Programmed Cell Death Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Synaptic Transmission Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Protein Metabolic Process Import Into Cell Regulation Of Cellular Component Organization Response To Stress