MBD5 and KIAA1549

Number of citations: 39 (PubMedID 12421765)
Data Source: HPRD (two hybrid)

		MBD5	KIAA1549
Name		methyl-CpG binding domain protein 5	KIAA1549
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Chromocenter Midbody Extracellular Exosome	Plasma Membrane Cilium Membrane Photoreceptor Connecting Cilium Cell Projection
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	Protein Binding
	Biological Process	Nervous System Development Regulation Of Multicellular Organism Growth Glucose Homeostasis Regulation Of Behavior Regulation Of Multicellular Organismal Process Positive Regulation Of Growth Hormone Receptor Signaling Pathway	None
Pathways		UCH proteinases	Signaling by BRAF and RAF1 fusions
Diseases		Non-syndromic autosomal dominant mental retardation	None
GWAS		Atrial fibrillation ( 29892015 ) Eosinophil percentage of white cells ( 32888494 ) Fourth ventricle volume ( 31530798 ) Loneliness ( 29970889 34054130 ) Loneliness (MTAG) ( 29970889 ) Monocyte count ( 32888494 ) Monocyte percentage of white cells ( 32888494 ) Pulse pressure ( 30578418 ) QT interval ( 29213071 ) Refractive error ( 32231278 ) Sociability score ( 34054130 ) Urate levels ( 31578528 )	Heel bone mineral density ( 30598549 )
Interacting Genes		6 interacting genes: APC FBXO7 H3C1 KIAA1549 SS18L2 ZNF76	10 interacting genes: CADPS CDC73 DST GNE ITSN2 LGALS4 MBD5 MYO5B SOD2 ZBTB16
Entrez ID		55777	57670
HPRD ID		11295	13873
Ensembl ID		ENSG00000204406	ENSG00000122778
Uniprot IDs		A0A1B0GW10 A0A2R8YDL9 Q9P267	Q9HCM3
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite	H Zone Antibacterial Peptide Biosynthetic Process Multicellular Organismal-level Chemical Homeostasis Response To Magnetism Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Response To Isolation Stress Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching Negative Regulation Of Membrane Hyperpolarization Regulation Of Fibroblast Proliferation Superoxide Dismutase Activity Acetylcholine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of Fibroblast Proliferation Erythrophore Differentiation Response To Silicon Dioxide Germ-line Stem Cell Division Positive Regulation Of NK T Cell Differentiation Type 2 Angiotensin Receptor Binding Male Germ-line Stem Cell Asymmetric Division Negative Regulation Of Myeloid Cell Differentiation Neuronal Dense Core Vesicle Membrane Vesicle-mediated Transport In Synapse CMP-N-acetylneuraminate Metabolic Process N-acylmannosamine Kinase Activity N-acetylneuraminate Biosynthetic Process N-acetylglucosamine Biosynthetic Process UDP-N-acetylglucosamine 2-epimerase Activity CMP-N-acetylneuraminate Biosynthetic Process Clathrin-dependent Synaptic Vesicle Endocytosis Positive Regulation Of Growth Hormone Receptor Signaling Pathway Regulation Of Membrane Hyperpolarization Regulation Of Fat Cell Differentiation Detection Of Oxygen Response To L-ascorbic Acid Positive Regulation Of MRNA 3'-end Processing Hemidesmosome Assembly Galactoside Binding Response To Superoxide Regulation Of NK T Cell Differentiation Endodermal Cell Fate Commitment