RBM22 and HNRNPUL1

Number of citations: 0 (PubMedID 22365833)
Data Source: BioGRID (two hybrid, two hybrid)

		RBM22	HNRNPUL1
Name		RNA binding motif protein 22	heterogeneous nuclear ribonucleoprotein U like 1
Structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Synapse Ribonucleoprotein Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding U6 SnRNA Binding Pre-mRNA Binding Metal Ion Binding Calcium-dependent Protein Binding	RNA Binding Protein Binding Enzyme Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of RNA Splicing Positive Regulation Of Protein Import Into Nucleus MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Protein Export From Nucleus Cellular Response To Xenobiotic Stimulus	Alternative MRNA Splicing, Via Spliceosome RNA Processing Response To Virus
Pathways		mRNA Splicing - Major Pathway	None
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025 ) Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 )	Apolipoprotein A1 levels ( 32203549 ) HDL cholesterol levels ( 32203549 ) Heel bone mineral density ( 28869591 ) Urinary albumin-to-creatinine ratio ( 31511532 )
Interacting Genes		45 interacting genes: AQR BAG4 BCAS2 BICD2 BMI1 CEBPA CEP55 CTBP1 CYSRT1 DMRTB1 EIF4ENIF1 ESS2 EXOSC7 EXOSC8 GIGYF1 GOLGA2 HNRNPUL1 HOMER3 HOOK1 KRT31 NCKIPSD NOA1 NXF1 OGT PQBP1 PRC1 PRMT2 PRNP PRPF39 PRPF6 RBFOX2 RBM4 RBPMS RNU6-1 RNU6-50P RNU6-6P SNRPA SNW1 TFIP11 TXNL4A VIM WBP4 YBX2 YTHDF1 YTHDF3	56 interacting genes: BRD7 CEBPA CRMP1 DMRTB1 DZIP3 EP300 ERG ERG28 EWSR1 FOXP1 FXR1 GIT2 HNRNPF HNRNPH2 HNRNPH3 IL7R ITCH KLHDC7B MAPK1IP1L MARS1 MED31 NEDD4 NXF1 NXF2 NXF3 PIAS2 PIAS4 PPIL1 PPP1R13B PRMT1 PRMT2 PRPF40A PTEN RBM22 RBM4 RBM4B ROPN1 RPA1 RPA2 SF1 SF3B4 SMN1 SMN2 SNRPB2 SNRPC SORBS3 SRSF9 TGM2 TLX3 TMEM132D TP53 TP53BP2 VPS37C WWP2 YAP1 ZNF207
Entrez ID		55696	11100
HPRD ID		10186	10428
Ensembl ID		ENSG00000086589	ENSG00000105323
Uniprot IDs		Q9NW64	A0A0A0MRA5 A8K3W4 B7Z4B8 Q9BUJ2
PDB IDs		2YTC 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P 7AAV 7ABG 7ABI 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD	1ZRJ
GO Terms Enriched among Interactors		RNA Splicing MRNA Metabolic Process MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Spliceosomal Complex RNA Binding RNA Metabolic Process Catalytic Step 2 Spliceosome Regulation Of MRNA Metabolic Process Cytoplasmic Stress Granule MRNA Binding Nuclear Speck Nucleic Acid Metabolic Process U4/U6 X U5 Tri-snRNP Complex Membraneless Organelle Assembly U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Nucleus Identical Protein Binding Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm U2-type Catalytic Step 2 Spliceosome Cellular Component Assembly Exoribonuclease Complex Regulation Of RNA Splicing Nucleic Acid Binding P-body Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Translational Initiation U4 SnRNA 3'-end Processing Regulation Of Long-term Synaptic Potentiation Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Translational Initiation Memory RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) U2-type Precatalytic Spliceosome TRNA Decay Nuclear MRNA Surveillance Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Processing Pre-mRNA Intronic Binding	Nucleoplasm RNA Splicing Nucleus Nucleic Acid Binding RNA Binding MRNA Processing RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Processing Spliceosomal Complex Macromolecule Metabolic Process Spliceosomal Complex Assembly Nuclear RNA Export Factor Complex PML Body Negative Regulation Of Cell Cycle Regulation Of RNA Splicing Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition P53 Binding Transcription Coregulator Activity Protein-RNA Complex Assembly Regulation Of Androgen Receptor Signaling Pathway Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition MRNA Binding MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Chromatin U1 SnRNP Protein-containing Complex Assembly Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Entrainment Of Circadian Clock By Photoperiod Poly(A)+ MRNA Export From Nucleus Cajal Body Regulation Of Cell Development Negative Regulation Of Mitotic Cell Cycle Nuclear Matrix Circadian Rhythm Regulation Of Macromolecule Metabolic Process Nuclear Androgen Receptor Binding