SHFL and KRTAP2-4

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid, two hybrid)

		SHFL	KRTAP2-4
Name		shiftless antiviral inhibitor of ribosomal frameshifting	keratin associated protein 2-4
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding Ribosome Binding Sequence-specific MRNA Binding	Protein Binding
	Biological Process	Regulation Of Translational Termination Response To Type I Interferon Response To Type II Interferon Response To Type III Interferon Response To Interferon-beta Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus Viral Translational Frameshifting Negative Regulation Of Translational Frameshifting	None
Pathways		None	Keratinization Keratinization
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		65 interacting genes: ADAMTSL4 CADPS CCDC136 CCNDBP1 CYSRT1 DRICH1 DTNBP1 DVL3 FHL5 HSF2BP IKZF1 INCA1 KLF15 KRT31 KRT40 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 LNX1 LURAP1 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NBPF19 NOTCH2NLA PCSK5 PDE4DIP PICK1 PPP2R5A SPRY2 SSX2IP TCF4 TENM4 TERF1 TLE5 TNS2 TRAF1 TRIB3 TRIM42 TRIM55 TRIM63 VWC2 ZNF835	100 interacting genes: ADAMTSL3 BAHD1 BCL6B BEX2 C11orf87 CATSPER1 CBX2 CHIC2 CNNM3 CREB5 CTSZ CXCL16 CYSRT1 DHX57 DMRT3 FAM161A GEMIN4 GGN HAPLN2 HHEX HOXA1 HOXB9 IGSF8 ITGB4 JOSD1 KLHL38 KRTAP1-1 KRTAP10-1 KRTAP10-5 KRTAP12-4 KRTAP2-3 KRTAP4-11 KRTAP4-12 KRTAP4-4 KRTAP5-11 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE5A LNX1 MCRS1 MOBP NBPF19 NKD1 NOTCH2NLA NPDC1 NUFIP2 OTX1 P2RY6 PHLDA1 PIGS PRKAB2 PTPMT1 RHBDL1 RPS28 SDC3 SHFL SPATA3 SPRED2 TFAP2D TMEM190 TNP2 TRIM42 TTPA VASN VWC2 YY1 ZBTB24 ZDHHC1 ZIM2 ZNF165 ZNF264 ZNF440 ZNF491 ZNF524 ZNF564 ZNF575 ZNF578 ZNF581 ZNF587 ZNF672 ZNF764 ZNF786 ZNF792
Entrez ID		55337	85294
HPRD ID		07747	13936
Ensembl ID		ENSG00000130813	ENSG00000213417
Uniprot IDs		Q9NUL5	P0C7H8 Q9BYR9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Keratin Filament Hair Cycle Identical Protein Binding Cytosol Protein Binding Interstitial Matrix	Keratinization Epidermis Development Intermediate Filament Keratin Filament Tissue Development Protein Binding DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Hair Cycle