TXNL4B and PNMA5

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		TXNL4B	PNMA5
Name		thioredoxin like 4B	PNMA family member 5
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex	Nucleus
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Positive Regulation Of Apoptotic Process
GWAS		Apolipoprotein B levels ( 32203549 ) Coronary artery disease ( 29212778 ) Hematocrit ( 32888494 ) Hemoglobin ( 32888494 ) LDL cholesterol levels ( 32203549 ) Lipoprotein (a) levels ( 33730874 ) Low density lipoprotein cholesterol levels ( 30718733 32154731 ) Medication use (HMG CoA reductase inhibitors) ( 31015401 ) Red blood cell count ( 32888494 ) Total cholesterol levels ( 30718733 ) Triglyceride levels ( 32154731 32203549 )	No GWAS studies recorded
Interacting Genes		13 interacting genes: AIPL1 ALKBH4 BHLHE40 MEOX1 MEOX2 PICK1 PLEKHF2 PNMA5 PRPF6 REL SF1 SPG21 TCF4	59 interacting genes: AP1M1 APPL1 ARPC4 CADPS CARD9 CCDC102B CCNC CDC23 CEP57L1 CETN2 CRACR2A CSTPP1 CTNNA3 DDX6 DRC4 DZIP1L EHHADH FOXH1 FSD2 GLIPR2 GOLGA6L9 GORASP2 GPRASP3 GRB2 GYS1 HOOK3 HSF2BP KIF9 KIFC3 KPNA2 LHX3 LNX1 MAGED1 MOAP1 MYO15B NTAQ1 PAX5 PNKP PNMA1 POLR3C PRKAA1 PSMA1 RAD23B SH3KBP1 SORBS3 SPG21 TBC1D22B TCEA2 TCEANC TNPO2 TTC23 TXNL4B UBASH3A VIM VPS28 ZBTB25 ZFYVE26 ZMYND19 ZRANB1
Entrez ID		54957	114824
HPRD ID		11655	06678
Ensembl ID		ENSG00000140830	ENSG00000198883
Uniprot IDs		Q9NX01	Q96PV4
PDB IDs		1XBS 3GIX 4IN0 8Y6O	Not available
GO Terms Enriched among Interactors		Somite Specification Segment Specification Somite Development DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Limb Development E-box Binding Spliceosomal Complex Assembly Farnesylated Protein Binding DNA N6-methyladenine Demethylase Activity Embryonic Pattern Specification Cleavage Furrow Ingression Positive Regulation Of Transcription By RNA Polymerase II Sclerotome Development Beta-catenin-TCF7L2 Complex Protein Farnesylation	XPC Complex Cytoskeleton Protein Binding Cytoplasm