COMMD8 and COXFA4L2

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		COMMD8	COXFA4L2
Name		COMM domain containing 8	cytochrome c oxidase hypoxia associated subunit FA4L2
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Mitochondrion Respiratory Chain Complex IV
	Molecular Function	Protein Binding NF-kappaB Binding	None
	Biological Process	Signal Transduction	None
Pathways		Neddylation	None
Drugs		None	NADH
GWAS		Risk-taking tendency (4-domain principal component model) ( 30643258 )	No GWAS studies recorded
Interacting Genes		5 interacting genes: AKR1C1 COMMD1 COXFA4L2 TMX2 ZNF474	14 interacting genes: ANXA9 C6orf62 COMMD8 DYNLL1 EIF3C ERG28 KAT5 KCNA4 LUC7L2 NUFIP2 PRKN QTRT1 SLC35F6 UBR1
Entrez ID		54951	56901
HPRD ID		13086	14249
Ensembl ID		ENSG00000169019	ENSG00000185633
Uniprot IDs		Q9NX08	Q9NRX3
PDB IDs		8F2R 8F2U 8P0W	Not available
GO Terms Enriched among Interactors		17-alpha,20-alpha-dihydroxypregn-4-en-3-one Dehydrogenase [NAD(P)+] Activity Steroid Dehydrogenase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Indanol Dehydrogenase Activity Sterol Homeostasis 3-beta-hydroxy-5-beta-steroid Dehydrogenase (NADP+) Activity 3-alpha-hydroxysteroid 3-dehydrogenase [NAD(P)+] Activity Cellular Response To Jasmonic Acid Stimulus Trans-1,2-dihydrobenzene-1,2-diol Dehydrogenase Activity Cholesterol Homeostasis Negative Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway Positive Regulation Of Cholesterol Import Positive Regulation Of Endosome To Plasma Membrane Protein Transport Ketosteroid Monooxygenase Activity Lipid Homeostasis Regulation Of Plasma Lipoprotein Particle Levels 5-alpha-androstane-3-beta,17-beta-diol Dehydrogenase (NADP+) Activity Regulation Of Cholesterol Import Daunorubicin Metabolic Process Carboxylic Acid Binding Androsterone Dehydrogenase [NAD(P)+] Activity Doxorubicin Metabolic Process Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Testosterone Dehydrogenase (NADP+) Activity Androstan-3-alpha,17-beta-diol Dehydrogenase (NAD+) Activity Bile Acid Binding Disulfide Oxidoreductase Activity Sodium Channel Inhibitor Activity Positive Regulation Of Endocytic Recycling Negative Regulation Of Sodium Ion Transmembrane Transport Intestinal Cholesterol Absorption Aldose Reductase (NADPH) Activity Plasma Membrane To Endosome Transport Alcohol Dehydrogenase (NADP+) Activity Negative Regulation Of Protein Localization To Cell Surface Intestinal Lipid Absorption Negative Regulation Of Cellular Response To Hypoxia Progesterone Metabolic Process Negative Regulation Of Sodium Ion Transport Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Lipid Binding Low-density Lipoprotein Particle Clearance Retinal Metabolic Process Respiratory Chain Complex IV Cul2-RING Ubiquitin Ligase Complex Copper Ion Homeostasis Positive Regulation Of Protein Localization To Cell Surface Regulation Of Endocytic Recycling Bile Acid And Bile Salt Transport Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Regulation Of Cellular Response To Hypoxia	None