CHCHD3 and NUDT3

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		CHCHD3	NUDT3
Name		coiled-coil-helix-coiled-coil-helix domain containing 3	nudix hydrolase 3
Structure		No pdb structure
GO Annotations	Cellular Component	SAM Complex Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Crista Junction MICOS Complex Extracellular Exosome MIB Complex	Nucleus Cytoplasm Cytosol Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding Phosphatase Binding Molecular Adaptor Activity	Magnesium Ion Binding Endopolyphosphatase Activity Protein Binding Zinc Ion Binding Diphosphoinositol-polyphosphate Diphosphatase Activity Pyrophosphatase Activity Hydrolase Activity Manganese Ion Binding Bis(5'-adenosyl)-hexaphosphatase Activity Bis(5'-adenosyl)-pentaphosphatase Activity Metal Ion Binding Inositol Diphosphate Tetrakisphosphate Diphosphatase Activity Inositol Diphosphate Pentakisphosphate Diphosphatase Activity Inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate Diphosphatase Activity Inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase Activity 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] Diphosphatase Activity 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity
	Biological Process	Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation	Cell-cell Signaling Diadenosine Polyphosphate Catabolic Process Diphosphoinositol Polyphosphate Metabolic Process Diphosphoinositol Polyphosphate Catabolic Process RNA Decapping Diadenosine Pentaphosphate Catabolic Process Diadenosine Hexaphosphate Catabolic Process Adenosine 5'-(hexahydrogen Pentaphosphate) Catabolic Process
Pathways		Mitochondrial protein import Cristae formation	Synthesis of pyrophosphates in the cytosol
GWAS		Chronotype ( 30696823 ) Food allergy ( 29030101 ) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441 ) Metabolite levels ( 23823483 ) Peanut allergy ( 29030101 ) Smoking status (ever vs never smokers) ( 30643258 ) Urinary potassium excretion ( 31409800 )	A body shape index ( 34021172 ) Atrial fibrillation ( 29892015 ) Body fat distribution (leg fat ratio) ( 30664634 ) Body fat distribution (trunk fat ratio) ( 30664634 ) Body mass index ( 20935630 29381148 ) Diastolic blood pressure ( 30224653 ) Estimated glomerular filtration rate ( 30604766 ) Fasting insulin ( 34059833 ) Height ( 25429064 31562340 19893584 ) Hip circumference ( 25673412 ) Hip circumference adjusted for BMI ( 34021172 ) Myeloproliferative neoplasms ( 33057200 ) Refractive error ( 32231278 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Interacting Genes		40 interacting genes: AMOTL2 ANKS1A ARMC7 BLZF1 CALCOCO2 CATSPERT CBY2 CCDC33 CCDC85B CEP72 CLPP CYSRT1 EFHC1 ENKD1 FANCL GMCL2 GOLGA2 KANK2 KRT40 KRTAP4-12 LMO1 LZTS2 NBPF19 NOTCH2NLA NTAQ1 NUDT3 NUTF2 NUTM1 PDE4DIP PPP1CB RAB3IP RBM11 RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 UBC USHBP1	36 interacting genes: ALAS1 APEX1 ARL6IP1 ASB13 CCL11 CHCHD3 DBN1 DDR1 DNAJA1 EEF1G FXYD3 HES1 ITFG1 MAF1 MCM5 MEX3B NR2C1 NUDT5 OAT PDCD5 PEX5 PRKD3 RAB17 REEP5 RNF126 RPL17 RPL8 RPLP1 SOX30 TNNT3 TUBA1A TUBGCP4 UBR1 VPS51 WDR74 XPNPEP1
Entrez ID		54927	11165
HPRD ID		13044	14849
Ensembl ID		ENSG00000106554	ENSG00000272325
Uniprot IDs		A4D1N4 B7Z1X9 C9JRZ6 Q9NX63	O95989
PDB IDs		Not available	2FVV 2Q9P 6PCK 6PCL 6WO7 6WO8 6WO9 6WOA 6WOB 6WOC 6WOD 6WOE 6WOF 6WOG 6WOH 6WOI 7TN4 8G9C 8G9D 8T98 8T99 8TF9 8TFA
GO Terms Enriched among Interactors		Spindle Organization Cytoplasm Microtubule Organizing Center Organization Cytoskeleton Centrosome Microtubule Cytoskeleton Organization Microtubule-based Process Centrosome Cycle	None