ZSCAN32 and ZKSCAN4

Number of citations: 97 (PubMedID 33961781)
Data Source: BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		ZSCAN32	ZKSCAN4
Name		zinc finger and SCAN domain containing 32	zinc finger with KRAB and SCAN domains 4
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway	Generic Transcription Pathway
GWAS		No GWAS studies recorded	Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Basal metabolic rate ( 31453325 ) Basal metabolic rate variance ( 31453325 ) Brain morphology (MOSTest) ( 32665545 ) Fish- and plant-related diet ( 32066663 ) Hip circumference adjusted for BMI ( 34021172 ) Refractive error ( 32231278 ) Schizophrenia ( 30285260 ) Subcortical volume (MOSTest) ( 32665545 )
Interacting Genes		17 interacting genes: KEAP1 MAD1L1 NTAQ1 PGBD1 PHF1 SCAND1 TRAF2 TXN2 ZKSCAN4 ZKSCAN7 ZNF24 ZNF396 ZNF446 ZSCAN12 ZSCAN16 ZSCAN22 ZSCAN29	19 interacting genes: CABP5 IL36RN LXN MAP1LC3A MDM4 MEOX2 OGT OSGIN1 PSMA6 TIAM1 TRIM39 ZKSCAN7 ZNF397 ZNF483 ZNF496 ZSCAN20 ZSCAN22 ZSCAN30 ZSCAN32
Entrez ID		54925	387032
HPRD ID		15791	15768
Ensembl ID		ENSG00000140987	ENSG00000187626
Uniprot IDs		Q9NX65	A0A0S2Z658 B7Z7H3 Q969J2
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Identical Protein Binding Metal Ion Binding Nucleus Sequence-specific Double-stranded DNA Binding TORC2 Complex Disassembly Sequence-specific DNA Binding MAD1 Complex Protein-N-terminal Glutamine Amidohydrolase Activity TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Mitotic Spindle Assembly Checkpoint MAD1-MAD2 Complex Protein-N-terminal Asparagine Amidohydrolase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Catabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Purine Ribonucleoside Triphosphate Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Primary Metabolic Process Mitophagy Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process