MS4A12 and FAM3A

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		MS4A12	FAM3A
Name		membrane spanning 4-domains A12	FAM3 metabolism regulating signaling molecule A
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Carbohydrate Binding
	Biological Process	Cell Surface Receptor Signaling Pathway	Glucose Metabolic Process ATP Biosynthetic Process Mitochondrion Organization Response To Glucose Gene Expression Antifungal Humoral Response Insulin Secretion Calcium Ion Homeostasis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Negative Regulation Of Antifungal Innate Immune Response
GWAS		Congenital heart disease (maternal effect) ( 28468790 ) Lymphocyte count ( 32888494 ) Supramarginal gyrus volume ( 31530798 )	Eosinophil count ( 32888494 ) Hemoglobin levels ( 26366553 ) Red blood cell traits ( 23446634 )
Interacting Genes		3 interacting genes: FAM3A MALL PLLP	9 interacting genes: ANP32B APP CLEC7A CREB3 MAL2 MEOX2 MS4A12 PACRGL UBC
Entrez ID		54860	60343
HPRD ID		08410	06505
Ensembl ID		ENSG00000071203	ENSG00000071889
Uniprot IDs		Q9NXJ0	D3DWX8 P98173 Q5HY75 Q9BU27
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Structural Constituent Of Myelin Sheath Myelination Axon Ensheathment Regulation Of Transcytosis Negative Regulation Of Antifungal Innate Immune Response Membrane Raft Compact Myelin Antifungal Humoral Response Myelin Assembly	Regulation Of Superoxide Anion Generation Response To Yeast Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Superoxide Anion Generation Regulation Of Superoxide Metabolic Process Regulation Of Monocyte Chemotaxis Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Amylin Binding Positive Regulation Of Toll Signaling Pathway Defense Response To Fungus Response To Fungus Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Deacetylase Activity Detection Of Yeast Detection Of Molecule Of Fungal Origin Positive Regulation Of Transport Positive Regulation Of Interleukin-1 Production Positive Regulation Of Chemokine Production Positive Regulation Of Type II Interferon Production Roof Of Mouth Development Acetylcholine Receptor Activator Activity Positive Regulation Of Mononuclear Cell Migration Regulation Of Cell Migration Positive Regulation Of Interleukin-6 Production Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Regulation Of Calcium-mediated Signaling Lipoprotein Particle Positive Regulation Of Protein Import Detection Of Fungus (1->3)-beta-D-glucan Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Chemokine Production Regulation Of Interleukin-1 Production Regulation Of Locomotion Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium