MFSD6 and AKAP19

Data Source: HiPPIP (Novel)

		MFSD6	AKAP19
Name		major facilitator superfamily domain containing 6	A-kinase anchoring protein 19
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I	None
GWAS		Arthritis (juvenile idiopathic) ( 33106285 ) Daytime sleep phenotypes ( 27126917 ) Estimated glomerular filtration rate ( 31015462 ) Medication use (thyroid preparations) ( 31015401 ) Platelet count ( 32888494 )	No GWAS studies recorded
Novel Interactors		7 novel interactors: AKAP19 ANKAR HIBCH MSTN OSGEPL1 STAT1 WDR75	1 novel interactors: MFSD6
Interacting Genes		37 interacting genes: ADIPOQ ALG8 APH1A APOL3 AQP7 C19orf18 CD79A CYB5R3 EBP ERGIC3 FAM209A GJA8 GJB2 GPR152 GPR42 GPX8 LY6E NKG7 PDCD1LG2 SELENOK SGPL1 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC39A2 SLC60A2 SMIM1 SSMEM1 STX12 SYNDIG1 TMEM179B TMEM237 TMEM242 TMEM258 TSPO2	11 interacting genes: ARMC7 BATF2 CENPP FBXO7 MYOD1 NFKBIL1 PRKAR1A PRKAR2B RALGPS1 TDP2 ZMIZ2
Entrez ID		54842	84281
HPRD ID		13369	14436
Ensembl ID		ENSG00000151690	ENSG00000187699
Uniprot IDs		B7Z7Y2 Q6ZSS7	Q9BSF0
PDB IDs		Not available	5HVZ
GO Terms Enriched among Interactors		Membrane Organic Hydroxy Compound Transport Bile Acid:sodium Symporter Activity Gap Junction-mediated Intercellular Transport	CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity Ubiquitin Protein Ligase Binding Protein Kinase A Catalytic Subunit Binding CAMP Binding Negative Regulation Of CAMP/PKA Signal Transduction Regulation Of CAMP/PKA Signal Transduction Ciliary Base Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite 5'-tyrosyl-DNA Phosphodiesterase Activity Tyrosyl-RNA Phosphodiesterase Activity Tyrosyl-DNA Phosphodiesterase Activity Myoblast Fate Determination Negative Regulation Of Intracellular Signal Transduction Response To Antipsychotic Drug Regulation Of Ral Protein Signal Transduction