PLCG1 and NCAM1

  • Number of citations: 0 (PubMedID 23061666)
  • Data Source: BioGRID (pull down)

PLCG1

NCAM1

Name phospholipase C gamma 1 neural cell adhesion molecule 1
Structure PDB 1HSQ PDB 2E3V
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
GWAS
  • Age at first sexual intercourse ( 34211149 27089180 )
  • Blood protein levels ( 30072576 )
  • Body mass index ( 25673413 )
  • Caffeine consumption from coffee ( 33287642 )
  • Caffeine consumption from coffee or tea ( 33287642 )
  • Cannabis use ( 27023175 30150663 )
  • Cardiac muscle measurement ( 21212386 )
  • Coffee consumption ( 31046077 )
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203 )
  • Depression ( 33859377 )
  • Entorhinal cortical thickness ( 21116278 )
  • Experiencing mood swings ( 29500382 )
  • Feeling miserable ( 29500382 )
  • Feeling tense ( 29500382 )
  • Frailty index ( 34431594 )
  • Gastroesophageal reflux disease ( 33608531 )
  • General factor of neuroticism ( 30867560 )
  • Gut microbiota (bacterial taxa) ( 27694959 )
  • Haemorrhoidal disease ( 33888516 )
  • Heel bone mineral density ( 30598549 28869591 )
  • Irritable bowel syndrome ( 33608531 )
  • LDL levels x SSRI levels interaction in schizophrenia or bipolar disorder ( 33824429 )
  • Macular thickness ( 30535121 )
  • Mood instability ( 31168069 )
  • Neurociticism ( 29500382 )
  • Number of sexual partners ( 30643258 )
  • Pulse pressure ( 27841878 )
  • Risk-taking tendency (4-domain principal component model) ( 30643258 )
  • Sense of smell ( 26632684 )
  • Smoking initiation ( 33082346 30617275 )
  • Smoking initiation (ever regular vs never regular) ( 30679032 )
  • Smoking status (current vs never) ( 33082346 )
  • Smoking status (ever vs never smokers) ( 30643258 )
  • Smoking status (heavy vs never) ( 26423011 )
  • Suicide attempts in depression or bipolar disorder ( 24964207 )
  • Systolic blood pressure ( 27841878 )
  • Total cholesterol levels x SSRI levels interaction in schizophrenia or bipolar disorder ( 33824429 )
Interacting Genes 112 interacting genes: ABL1 AGAP2 AGTR1 AKT1 ALK AR ARHGAP32 ARHGEF5 AXL BAG3 BCR BLNK BTK CBL CD22 CD28 CTSS DAB1 DAPP1 DDR1 DGKZ DNM1 DOK1 EEF1A1 EGFR EPHB2 EPOR ERBB2 ERBB3 ERBB4 FGFR1 FGFR2 FGFR4 FLT1 FYN GAB1 GAB2 GHR GIT1 GRAP GRB2 GRIN1 GRIN2A GRIN2B GSN GTF2H1 HCK INPP5D INSR IRS2 ITK KDR KHDRBS1 KIT LAT LAT2 LCK LCP2 LIFR LYN MAPT MET MST1R NCAM1 NCK1 NPM1 NTRK1 NTRK2 NTRK3 PAK1 PDGFRA PDGFRB PECAM1 PICALM PITPNA PKN2 PLD2 PRKD1 PRMT8 PTK2 PTPN11 PTPRJ RACK1 RBM11 RET RHOA RHOU SELE SH2D2A SH3BP2 SHB SHC1 SNAP91 SOCS7 SOS1 SOS2 SRC SYK SYN1 SYNCRIP TEC TNK1 TRIM14 TRPC3 TRPM7 TUB USO1 VAV1 VAV3 VIL1 WAS ZAP70 19 interacting genes: ATXN1 BDNF EGFR FGFR1 FYN GDNF GFRA1 L1CAM NCAN PLCG1 PPP1CA PRNP RHEB SPTB ST8SIA2 ST8SIA3 ST8SIA4 TUBB UCHL1
Entrez ID 5335 4684
HPRD ID 01398 00301
Ensembl ID ENSG00000124181 ENSG00000149294
Uniprot IDs P19174 A0A087WWD4 H7BYX6 P13591
PDB IDs 1HSQ 2HSP 4EY0 4FBN 7NXE 2E3V 2HAZ 2VKW 2VKX 3MTR 5AEA 5LKN
GO Terms Enriched among Interactors