DNAJB11 and ANKZF1

Number of citations: 0 (PubMedID 21900206)
Data Source: BioGRID (two hybrid)

		DNAJB11	ANKZF1
Name		DnaJ heat shock protein family (Hsp40) member B11	ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Chaperone Complex Protein Folding Chaperone Complex	Cytoplasm Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Unfolded Protein Binding Misfolded Protein Binding	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding Catalytic Activity, Acting On A TRNA
	Biological Process	Protein Folding MRNA Modification Positive Regulation Of ATP-dependent Activity Negative Regulation Of Neurogenesis Protein Maturation	TRNA 3'-terminal CCA Addition Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins ERAD Pathway TRNA 3'-end Processing Cellular Response To Hydrogen Peroxide Rescue Of Stalled Ribosome
Pathways		XBP1(S) activates chaperone genes	Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		24 interacting genes: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3	10 interacting genes: APP AURKB CA2 CRK CTTN DNAJB11 NRSN2 STAT6 UBC YWHAE
Entrez ID		51726	55139
HPRD ID		07485	07673
Ensembl ID		ENSG00000090520	ENSG00000163516
Uniprot IDs		Q9UBS4	B8ZZS4 Q9H8Y5
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Cellular Response To Stress Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Oxidative Stress Positive Regulation Of Dendrite Development Regulation Of Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Cellular Response To Oxidative Stress Misfolded Protein Binding Biomineral Tissue Development Response To Endoplasmic Reticulum Stress ERAD Pathway	Response To Yeast Mitotic Spindle Midzone Regulation Of Immune Response Ephrin Receptor Binding Positive Regulation Of Supramolecular Fiber Organization Regulation Of Innate Immune Response Neuron Projection Organization Regulation Of Toll-like Receptor Signaling Pathway Response To Nerve Growth Factor Dendrite Development Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Immune Response Negative Regulation Of Immune System Process Regulation Of T Cell Migration Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Defense Response Growth Cone Lamellipodium Regulation Of Immune System Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Lymphocyte Migration Clathrin-coated Pit Response To Fungus Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Dipeptide Transmembrane Transport Cyanamide Hydratase Activity Helper T Cell Diapedesis Cerebral Cortex Development Hippocampus Development Signaling Adaptor Activity Protein Phosphorylated Amino Acid Binding Ubiquitin Protein Ligase Binding Scaffold Protein Binding Response To Cholecystokinin Mammary Gland Morphogenesis Regulation Of Heart Rate By Hormone Mitotic Sister Chromatid Biorientation Repair Of Mitotic Kinetochore Microtubule Attachment Defect Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Supramolecular Fiber Organization PTB Domain Binding Signaling Receptor Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Monoatomic Cation Homeostasis Regulation Of Monoatomic Ion Transport Enzyme Binding