OAZ3 and OAZ1

Number of citations: 42 (PubMedID 15355308)
Data Source: HPRD (two hybrid)

		OAZ3	OAZ1
Name		ornithine decarboxylase antizyme 3	ornithine decarboxylase antizyme 1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Sperm Flagellum Blood Microparticle	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity Ankyrin Repeat Binding	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Polyamine Biosynthetic Process Spermatogenesis Positive Regulation Of Protein Catabolic Process Negative Regulation Of Stress Fiber Assembly Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport	Biogenic Amine Metabolic Process Polyamine Biosynthetic Process Positive Regulation Of Protein Catabolic Process Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs		None	Ornithine
GWAS		Asthma ( 31619474 ) Carotid plaque burden ( 28282560 ) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566 ) Insomnia symptoms (never/rarely vs. usually) ( 30804566 )	No GWAS studies recorded
Interacting Genes		14 interacting genes: AZIN2 BLZF1 C1orf94 GGN IKZF3 L3MBTL3 OAZ1 POMC POU6F2 REL SMAD1 TEPSIN ZBTB42 ZNF620	13 interacting genes: AGTR1 ATXN1 EGFR HTR2B MYCBP2 NLGN3 NRIP1 OAZ2 OAZ3 ODC1 PIAS4 PSMB4 SMAD1
Entrez ID		51686	4946
HPRD ID		18670	03346
Ensembl ID		ENSG00000143450	ENSG00000104904
Uniprot IDs		A0A0G2JH29 H0Y7Y4 Q9UMX2	J3QQY4 P54368
PDB IDs		Not available	4ZGY 4ZGZ 5BWA
GO Terms Enriched among Interactors		Polyamine Biosynthetic Process Polyamine Metabolic Process Regulation Of DNA-templated Transcription Mesodermal Cell Fate Commitment Regulation Of Primary Metabolic Process Homomeric SMAD Protein Complex Osteoblast Fate Commitment Regulation Of RNA Biosynthetic Process Ubiquitin Protein Ligase Binding DNA-binding Transcription Factor Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Amine Biosynthetic Process Ornithine Decarboxylase Inhibitor Activity Biogenic Amine Biosynthetic Process Amine Metabolic Process Negative Regulation Of Polyamine Transmembrane Transport Biogenic Amine Metabolic Process Positive Regulation Of Neutrophil Mediated Killing Of Fungus Positive Regulation Of Oxytocin Production Response To Melanocyte-stimulating Hormone Cis-Golgi Network Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Methylation-dependent Protein Binding Ornithine Decarboxylase Activator Activity Arginine Decarboxylase Activity Granular Vesicle Agmatine Biosynthetic Process Ornithine Decarboxylase Activity Positive Regulation Of Polyamine Transmembrane Transport Putrescine Biosynthetic Process From Arginine, Via Ornithine Trans-Golgi Network Membrane Organization Coated Vesicle Membrane Regulation Of Transcription By RNA Polymerase II Cellular Pigmentation Type 1 Melanocortin Receptor Binding Type 4 Melanocortin Receptor Binding Positive Regulation Of Killing Of Cells Of Another Organism Type 3 Melanocortin Receptor Binding NF-kappaB Complex Ornithine Metabolic Process Anti-Mullerian Hormone Receptor Signaling Pathway Regulation Of RNA Metabolic Process Putrescine Biosynthetic Process Regulation Of Corticosterone Secretion Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity	Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Polyamine Biosynthetic Process Biogenic Amine Metabolic Process Polyamine Metabolic Process Amine Metabolic Process Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Positive Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Viral Translational Frameshifting Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process System Process Transcription Coregulator Activity Cellular Response To Estradiol Stimulus Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cell Population Proliferation Positive Regulation Of Epithelial Cell Proliferation Angiotensin Type I Receptor Activity Animal Organ Development Hair Follicle Development Regulation Of Protein Localization Nervous System Process Multivesicular Body, Internal Vesicle Lumen GTP Cyclohydrolase I Activity Ovarian Follicle Rupture Regulation Of Cellular Response To Stress MAPK Cascade Social Behavior Positive Regulation Of MiRNA Transcription Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of MiRNA Metabolic Process Bradykinin Receptor Binding Learning Or Memory Shc-EGFR Complex Endocytic Vesicle Homomeric SMAD Protein Complex Circadian Regulation Of Gene Expression Limb Epidermis Development Regulation Of Cell Population Proliferation Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Cytoplasm Cognition Regulation Of MiRNA Transcription Positive Regulation Of Protein Kinase C Signaling Ubiquitin Protein Ligase Binding