SARAF and ABCD4

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		SARAF	ABCD4
Name		store-operated calcium entry associated regulatory factor	ATP binding cassette subfamily D member 4
Structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum-plasma Membrane Contact Site	Lysosome Lysosomal Membrane Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane ATP-binding Cassette (ABC) Transporter Complex
	Molecular Function	Protein Binding	Nucleotide Binding Long-chain Fatty Acid Transmembrane Transporter Activity Protein Binding ATP Binding ABC-type Vitamin B12 Transporter Activity ATP Hydrolysis Activity ATPase-coupled Transmembrane Transporter Activity Identical Protein Binding ABC-type Transporter Activity
	Biological Process	Monoatomic Ion Transport Calcium Ion Transport Regulation Of Store-operated Calcium Entry	Fatty Acid Beta-oxidation Peroxisome Organization Cobalamin Metabolic Process Cobalamin Transport Long-chain Fatty Acid Import Into Peroxisome Very Long-chain Fatty Acid Catabolic Process Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor
Pathways		None	Defective ABCD4 causes MAHCJ Uptake of dietary cobalamins into enterocytes Transport of RCbl within the body
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		7 interacting genes: ABCD4 HTR4 IFIT5 PDCD6 RIBC2 SAT1 SNX15	5 interacting genes: DLEU1 HSPB2 PEA15 SARAF XRCC6
Entrez ID		51669	5826
HPRD ID		08651	04446
Ensembl ID		ENSG00000133872	ENSG00000119688
Uniprot IDs		A0A140VK59 Q96BY9	O14678
PDB IDs		6O2U 6O2V 6O2W	6JBJ
GO Terms Enriched among Interactors		Large Intestinal Transit ABC-type Vitamin B12 Transporter Activity Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding	None