GET4 and KIFC2

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		GET4	KIFC2
Name		guided entry of tail-anchored proteins factor 4	kinesin family member C2
Structure			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Nucleolus Cytoplasm Cytosol BAT3 Complex	Cytoplasm Cytoskeleton Kinesin Complex Microtubule Dendrite Cytoplasm
	Molecular Function	Protein Binding Protein-folding Chaperone Binding Protein Carrier Chaperone	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Protein Stability ERAD Pathway Maintenance Of Unfolded Protein Protein Insertion Into ER Membrane Tail-anchored Membrane Protein Insertion Into ER Membrane	Microtubule-based Movement Axon Guidance Synaptic Vesicle Transport Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	COPI-dependent Golgi-to-ER retrograde traffic Kinesins
GWAS		PR interval ( 32439900 )	Blood metabolite levels ( 26401656 ) Educational attainment ( 25201988 )
Interacting Genes		29 interacting genes: AIRIM AKT1 ATP5PD CAPNS1 CDKN1A CEBPA CEP126 DUSP21 EEF1G ENKD1 FBN1 FBXO7 FLYWCH2 GIT2 KAT5 KIFC2 KRTAP9-3 NUP85 PLK1 PRKAB2 PRKCSH PTMS SDCBP SEC61B SNCAIP SOD2 TMEM256 TTR UBAC2	4 interacting genes: GET4 MAPK8IP2 TAB1 TEAD3
Entrez ID		51608	90990
HPRD ID		12909	13916
Ensembl ID		ENSG00000239857	ENSG00000167702
Uniprot IDs		Q7L5D6	A0A2R8YEU8 Q96AC6
PDB IDs		6AU8 7RU9 7RUA 7RUC	Not available
GO Terms Enriched among Interactors		Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Localization Microtubule Cytoskeleton Organization Involved In Mitosis Establishment Of Mitotic Spindle Orientation Establishment Of Spindle Localization Response To Nutrient Levels Spindle Localization Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Localization To Nucleus Establishment Of Protein Localization To Organelle Carbohydrate Homeostasis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Glucose Homeostasis Protein Localization To Endoplasmic Reticulum Regulation Of Macroautophagy Microtubule-based Process Positive Regulation Of Protein Modification Process	None