NIN and RTRAF

Number of citations: 0 (PubMedID 15147888)
Data Source: HPRD (in vivo, two hybrid, in vitro)

		NIN	RTRAF
Name		ninein	RNA transcription, translation and transport factor
Structure		No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Cytoskeleton Microtubule Cytoplasmic Microtubule Plasma Membrane Axon Dendrite Ciliary Basal Body Axonal Growth Cone Apical Part Of Cell Mitotic Spindle Mitotic Spindle Pole Ciliary Transition Fiber Centriolar Subdistal Appendage	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Perinuclear Region Of Cytoplasm TRNA-splicing Ligase Complex Mitotic Spindle
	Molecular Function	Nucleotide Binding Calcium Ion Binding Protein Binding GTP Binding Microtubule Minus-end Binding	RNA Polymerase II Complex Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Intracellular Protein Localization Centriole-centriole Cohesion Corpus Callosum Morphogenesis Corticospinal Tract Morphogenesis Microtubule Anchoring At Centrosome Collateral Sprouting Positive Regulation Of Axonogenesis Centrosome Localization Centrosome-templated Microtubule Nucleation	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Negative Regulation Of Protein Kinase Activity Positive Regulation Of Transcription By RNA Polymerase II RNA Transport
Pathways		None	tRNA processing in the nucleus
GWAS		Alanine aminotransferase levels ( 33547301 34315874 ) Aspartate aminotransferase levels ( 34315874 ) Asthma (time to childhood onset) x early life tobacco smoke interaction ( 31379025 ) Cognitive performance ( 20125193 ) Diastolic blood pressure ( 30578418 ) Lupus nephritis in systemic lupus erythematosus ( 24925725 ) Mean platelet volume ( 27863252 ) Periodontal disease-related phenotype (Socransky) ( 24347629 ) Pulse pressure ( 30578418 ) Rectal cancer ( 33632709 ) Refractive error ( 32231278 ) Schizophrenia ( 33169155 ) Stroke ( 32693751 ) Systolic blood pressure ( 30578418 )	No GWAS studies recorded
Interacting Genes		17 interacting genes: ABI1 AUNIP AURKA BICD1 GSK3B GTSE1 KLC1 PIAS1 PRKACA PRPF6 RBM10 RTRAF SNW1 SUMO1 UBE2I UTP14A YWHAE	7 interacting genes: CEBPA DISC1 GLP1R MTNR1A NIN PCNT PSORS1C2
Entrez ID		51199	51637
HPRD ID		09785	16615
Ensembl ID		ENSG00000100503	ENSG00000087302
Uniprot IDs		C9J066 E9PN67 Q5XUU0 Q8N4C6	Q549M8 Q9Y224
PDB IDs		Not available	7P3A
GO Terms Enriched among Interactors		Regulation Of Nucleocytoplasmic Transport Nuclear Speck Ubiquitin Protein Ligase Binding Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Glutamatergic Synapse Presynaptic Cytosol Postsynaptic Cytosol Regulation Of Protein Export From Nucleus Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Small Protein Activating Enzyme Binding PML Body Centrosome Peptidyl-serine Phosphorylation Regulation Of Intracellular Transport Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Localization To Centrosome Regulation Of Intracellular Protein Transport Cellular Response To Heat Protein Sumoylation Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Processing Regulation Of Protein Localization To Centrosome RNA Binding Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Protein Localization To Organelle Dynactin Binding Positive Regulation Of Protein Catabolic Process Enzyme Binding Response To Heat Positive Regulation Of Intracellular Protein Transport Intracellular Potassium Ion Homeostasis Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Localization Transcription Factor Binding SUMO Transferase Activity Membraneless Organelle Assembly Cytoskeleton Negative Regulation Of Metabolic Process Regulation Of Cellular Localization Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Protein Metabolic Process Nuclear Export Negative Regulation Of Nucleobase-containing Compound Metabolic Process	Microtubule Nucleation Axonal Growth Cone CHOP-C/EBP Complex Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Glucagon-like Peptide 1 Receptor Activity Glucagon Receptor Activity Microtubule Microtubule Organizing Center Cell Projection Organization Cytoskeleton Organization Microtubule Cytoskeleton Organization Axon Basal Dendrite Morphogenesis Basal Dendrite Arborization Pyramidal Neuron Migration To Cerebral Cortex Positive Regulation Of Axonogenesis Central Region Of Growth Cone Centrosome-templated Microtubule Nucleation Organelle Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Response To Psychosocial Stress Melatonin Receptor Activity Centrosome Centriole Cytoskeleton Axonogenesis Radial Glia-guided Pyramidal Neuron Migration Regulation Of Axonogenesis Corticospinal Tract Morphogenesis Microtubule Nucleation By Microtubule Organizing Center Corpus Callosum Morphogenesis Response To Phenylpropanoid Fat Cell Proliferation Post-translational Protein Targeting To Membrane, Translocation Receptor Complex Molecular Adaptor Activity Dendritic Growth Cone Cerebral Cortex Radial Glia-guided Migration Ciliary Transition Fiber Positive Regulation Of Proteolysis