APIP and PDZD4

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		APIP	PDZD4
Name		APAF1 interacting protein	PDZ domain containing 4
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cell Cortex
	Molecular Function	Protein Binding Zinc Ion Binding Lyase Activity Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity Metal Ion Binding	None
	Biological Process	Apoptotic Process Amino Acid Biosynthetic Process Methionine Biosynthetic Process L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptotic Inflammatory Response Regulation Of ERK1 And ERK2 Cascade	None
Pathways		Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity	None
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326 ) Cystic fibrosis severity ( 21602797 ) Gamma glutamyl transferase levels ( 29403010 33339817 ) Lung disease severity in cystic fibrosis ( 26417704 ) Prostate-specific antigen levels ( 28139693 ) Systemic lupus erythematosus ( 19838195 )	No GWAS studies recorded
Interacting Genes		18 interacting genes: APAF1 BAZ2B CFAP206 GORASP2 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 VIM VPS25 ZBTB25	15 interacting genes: APIP APP ASCL4 CEP76 CTDSP1 DNMT3L DYDC1 ENKD1 GFI1B IKZF3 JRK KCTD9 MTUS2 TRAF2 TRAF3
Entrez ID		51074	57595
HPRD ID		14725	06601
Ensembl ID		ENSG00000149089	ENSG00000067840
Uniprot IDs		Q96GX9	B3KW03 Q17RL8 Q76G19
PDB IDs		4M6R	Not available
GO Terms Enriched among Interactors		None	Thioesterase Binding CD40 Receptor Complex