NDUFB8 and EIF2B3

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		NDUFB8	EIF2B3
Name		NADH:ubiquinone oxidoreductase subunit B8	eukaryotic translation initiation factor 2B subunit gamma
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Respiratory Chain Complex I	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Cytoplasmic Translational Initiation Translation Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Response To Peptide Hormone T Cell Receptor Signaling Pathway
Pathways		Mitochondrial protein import Mitochondrial protein import Respiratory electron transport Complex I biogenesis	Recycling of eIF2:GDP
Drugs		NADH	None
Diseases		None	Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS		Brain morphology (MOSTest) ( 32665545 ) Palmitoleic acid (16:1n-7) levels ( 23362303 )	Platelet distribution width ( 32888494 )
Interacting Genes		6 interacting genes: ATP6V0D2 CACNA1A EIF2B3 PFN2 PIM2 ZAP70	5 interacting genes: EIF2S1 EIF2S2 GOLM1 NDUFB8 STC2
Entrez ID		4714	8891
HPRD ID		11886	09379
Ensembl ID		ENSG00000166136	ENSG00000070785
Uniprot IDs		O95169	Q9HA31 Q9NR50
PDB IDs		5XTC 5XTD 5XTH 5XTI	6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z 7D43 7D44 7D45 7D46 7F64 7F66 7F67 7KMF 7L70 7L7G 7RLO 7TRJ 7VLK 8TQO 8TQZ
GO Terms Enriched among Interactors		None	Eukaryotic Translation Initiation Factor 2 Complex Endoplasmic Reticulum Unfolded Protein Response Translation Initiation Ternary Complex Translation Initiation Factor Activity Histone H3K36me2/H3K36me3 Demethylase Activity Translational Initiation Response To Manganese-induced Endoplasmic Reticulum Stress Glial Limiting End-foot N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Male Germ Cell Proliferation