MYO9A and POLR2M

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		MYO9A	POLR2M
Name		myosin IXA	RNA polymerase II subunit M
Structure		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Actin Filament Membrane Myosin Complex Unconventional Myosin Complex Growth Cone Cell Projection Axonal Growth Cone Synapse	DNA-directed RNA Polymerase Complex Nucleus Nuclear Envelope RNA Polymerase II, Core Complex I Band Neuronal Cell Body Transcription Preinitiation Complex
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding GTPase Activator Activity Protein Binding ATP Binding Zinc Ion Binding Metal Ion Binding Actin Filament Binding	RNA Polymerase II Complex Binding Transcription Elongation Factor Activity
	Biological Process	Signal Transduction Visual Perception Cell Junction Assembly Cell Junction Organization Intracellular Signal Transduction Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Neuron Projection Arborization	Transcription Elongation By RNA Polymerase II Maintenance Of ER Location
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOV GTPase cycle	None
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223 ) Height ( 20881960 ) Macular thickness ( 30535121 ) Metabolite levels (HVA/MHPG ratio) ( 23319000 ) Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209 ) Red blood cell count ( 27863252 ) Serum uric acid levels ( 30993211 ) Triglyceride levels ( 30108155 32203549 ) Urate levels ( 31578528 )	Body mass index ( 28552196 ) Seasonality ( 25562672 )
Interacting Genes		5 interacting genes: CDC42 ERBB2 MTNR1A POLR2M RHOA	22 interacting genes: AHSP ANKHD1 APOD CEBPG CEP126 DAPK1 DGKZ HIGD1B LRRK1 LRRK2 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		4649	81488
HPRD ID		05341	07575
Ensembl ID		ENSG00000066933	ENSG00000255529
Uniprot IDs		B2RTY4	P0CAP2 Q6EEV4
PDB IDs		Not available	6DRD
GO Terms Enriched among Interactors		Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Epithelial Cell Apical/basal Polarity Establishment Of Epithelial Cell Polarity Wnt Signaling Pathway, Planar Cell Polarity Pathway Substantia Nigra Development Establishment Or Maintenance Of Apical/basal Cell Polarity Semaphorin-plexin Signaling Pathway Positive Regulation Of Stress Fiber Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cytokinesis Membrane Invagination Non-canonical Wnt Signaling Pathway Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Actin Filament Bundle Assembly Neural Nucleus Development G Protein Activity Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Cell Junction Organization Mitotic Cleavage Furrow Formation Regulation Of Cytokinesis Collagen Type XV Trimer Maintenance Of ER Location Positive Regulation Of Cell Division Establishment Of Cell Polarity Cell Periphery Positive Regulation Of Cell Adhesion Regulation Of Stress Fiber Assembly Ruffle Membrane Aortic Valve Formation Positive Regulation Of Vascular Associated Smooth Muscle Contraction Endothelial Tube Lumen Extension Glial Cell Differentiation Skeletal Muscle Satellite Cell Migration GBD Domain Binding Storage Vacuole ERBB3:ERBB2 Complex Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Kinase Activity Striated Muscle Tissue Development Positive Regulation Of Kinase Activity Beta Selection Endothelin Receptor Signaling Pathway Involved In Heart Process RNA Polymerase I Core Binding Muscle Tissue Development Bone Trabecula Morphogenesis Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Cell Growth	None