MPP3 and RAB31

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		MPP3	RAB31
Name		MAGUK p55 scaffold protein 3	RAB31, member RAS oncogene family
Structure		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Adherens Junction Membrane Apical Plasma Membrane Anchoring Junction	Phagocytic Cup Cytoplasm Endosome Early Endosome Late Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endomembrane System Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Trans-Golgi Network Membrane Early Phagosome Membrane Phagocytic Vesicle
	Molecular Function	Protein Binding PDZ Domain Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding
	Biological Process	None	Intracellular Protein Transport Endocytosis Receptor Internalization Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Golgi Vesicle Transport Positive Regulation Of Phagocytosis, Engulfment Phagosome Maturation
Pathways		None	Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
GWAS		HDL cholesterol levels ( 30698716 ) HDL cholesterol levels in current drinkers ( 30698716 ) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716 ) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716 ) Triglyceride levels in current drinkers ( 30698716 ) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716 ) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716 ) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535 ) Triglycerides ( 24097068 )	Age at first sexual intercourse ( 27089180 ) Basophil count ( 32888494 ) Blood pressure (age interaction) ( 24954895 ) Bone fracture in osteoporosis ( 28580392 ) Dupuytren's disease ( 28886342 ) Lung adenocarcinoma ( 28604730 )
Interacting Genes		37 interacting genes: APP ARL2BP BTBD1 CADM1 CCDC137 CRABP1 ERBIN EZR FAM171B FBXO7 GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PKNOX1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TIRAP TMEM37 TRAF2 TRIM41 ZNF655 ZPR1	6 interacting genes: ALS2CL EEA1 EGFR MAPK6 MPP3 OCRL
Entrez ID		4356	11031
HPRD ID		03069	05751
Ensembl ID		ENSG00000161647	ENSG00000168461
Uniprot IDs		D3DX46 Q13368	Q13636
PDB IDs		Not available	2FG5
GO Terms Enriched among Interactors		None	Early Endosome Membrane MAPK Cascade Kinase Activity Protein Kinase Activity Epidermal Growth Factor Binding Positive Regulation Of Protein Kinase C Signaling Epidermal Growth Factor Receptor Activity Shc-EGFR Complex Multivesicular Body, Internal Vesicle Lumen Inositol Phosphate Phosphatase Activity Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol Bisphosphate Phosphatase Activity Phosphatidylinositol Phosphate 4-phosphatase Activity Septin Cytoskeleton Postsynaptic Early Endosome Axonal Spine Chemical Synaptic Transmission, Postsynaptic Synaptic Vesicle To Endosome Fusion