MAN2A2 and LUC7L2

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		MAN2A2	LUC7L2
Name		mannosidase alpha class 2A member 2	LUC7 like 2, pre-mRNA splicing factor
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Nucleus Nucleoplasm U1 SnRNP Nuclear Speck U2-type Prespliceosome
	Molecular Function	Catalytic Activity Alpha-mannosidase Activity Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase Activity Protein Binding Mannosidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Hydrolase Activity, Hydrolyzing N-glycosyl Compounds Carbohydrate Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Enzyme Binding
	Biological Process	Carbohydrate Metabolic Process Mannose Metabolic Process Protein Glycosylation N-glycan Processing	MRNA Splice Site Recognition
Pathways		Intra-Golgi traffic Reactions specific to the complex N-glycan synthesis pathway	None
GWAS		Attention deficit hyperactivity disorder ( 18839057 ) Brain morphology (MOSTest) ( 32665545 ) Caffeine consumption from coffee ( 33287642 ) Schizophrenia ( 25056061 29483656 )	Diisocyanate-induced asthma ( 25918132 ) Left ventricular end-diastolic volume (MTAG) ( 33495596 ) Left ventricular end-systolic volume (MTAG) ( 33495596 )
Interacting Genes		6 interacting genes: CHD3 ELP1 ENO3 GIT1 LUC7L2 VIM	67 interacting genes: AIMP2 ALB ANKHD1 ANTKMT AP2M1 APP APPBP2 ATF7IP ATRX C1orf35 CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 COXFA4L2 DHX8 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 HOXA1 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NEDD4 NFYA NKAP NSF NUTF2 OFD1 OGT PDPK1 PEA15 PIK3R3 PRPF38A PTCD3 PTN RHOA SAT1 SETDB1 SNRNP48 SRPK2 SRRM4 SRSF6 SRSF7 SRSF8 SVIL ULK2 UNC119 WASHC3 WEE2-AS1 YWHAG ZCCHC10 ZRSR2
Entrez ID		4122	51631
HPRD ID		02994	17456
Ensembl ID		ENSG00000196547	ENSG00000146963
Uniprot IDs		A0A0C4DGL1 H0YNG5 P49641	Q9Y383
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Positive Regulation Of Microtubule Polymerization Centrosome Cycle Regulation Of Microtubule Polymerization Scaffold Protein Binding Negative Regulation Of ARF Protein Signal Transduction Microtubule Organizing Center Organization Positive Regulation Of Protein Polymerization Regulation Of Microtubule Polymerization Or Depolymerization Focal Adhesion Cellular Response To Lipid Structural Constituent Of Postsynaptic Specialization	Protein Binding Negative Regulation Of Long-term Synaptic Potentiation Cytosol RNA Splicing Protein-containing Complex Organization Regulation Of Long-term Synaptic Potentiation Presynapse MRNA Processing Nucleus Cellular Component Assembly Low-density Lipoprotein Particle Mediated Signaling Regulation Of MRNA Splicing, Via Spliceosome Establishment Of Protein Localization Positive Regulation Of Neuron Apoptotic Process Microtubule Cytoskeleton Organization Involved In Mitosis Intracellular Protein Localization Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Binding Positive Regulation Of Protein Localization To Cilium Insulin Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Protein-containing Complex Assembly Microtubule Organizing Center Organization Positive Regulation Of Cilium Assembly Regulation Of MRNA Metabolic Process Nucleic Acid Binding Microtubule Associated Complex Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Spindle Organization Organelle Assembly MRNA Binding MRNA Metabolic Process Positive Regulation Of Organelle Assembly Regulation Of Protein Localization To Cilium Membraneless Organelle Assembly Regulation Of RNA Splicing Establishment Of Vesicle Localization