ARSA and CLEC4G

Number of citations: 0 (PubMedID 18624398)
Data Source: BioGRID (two hybrid)

		ARSA	CLEC4G
Name		arylsulfatase A	C-type lectin domain family 4 member G
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Lumen Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Arylsulfatase Activity Cerebroside-sulfatase Activity Calcium Ion Binding Protein Binding Sulfuric Ester Hydrolase Activity Hydrolase Activity Metal Ion Binding	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Polysaccharide Binding Pattern Recognition Receptor Activity Fructose Binding Carbohydrate Derivative Binding Virus Coreceptor Activity Glycosylated Region Protein Binding
	Biological Process	Lipid Metabolic Process	T Cell Mediated Immunity Negative Regulation Of T Cell Mediated Immunity Immune Response Immature T Cell Proliferation In Thymus Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of T Cell Proliferation Alpha-beta T Cell Proliferation Negative Regulation Of Alpha-beta T Cell Proliferation Symbiont Entry Into Host Cell Positive Regulation Of Viral Life Cycle
Pathways		The activation of arylsulfatases Neutrophil degranulation Glycosphingolipid catabolism	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		4-Nitrocatechol sulfate 2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid	None
Diseases		Metachromatic leukodystrophy (MLD)	None
GWAS		Aspartate aminotransferase levels ( 33547301 ) Fibrinogen ( 23969696 ) Fibrinogen levels ( 28107422 ) QT interval (ambient particulate matter interaction) ( 28749367 ) Urinary metabolite levels in chronic kidney disease ( 31959995 ) vWF and FVIII levels ( 30586737 )	Post bronchodilator FEV1 ( 26634245 )
Interacting Genes		18 interacting genes: ANXA11 BMPR2 CAMK2B CCDC22 CETN2 CLEC4G CTSL EID2B FOXI1 GAL3ST1 PKN1 POU1F1 PPIC PROP1 RHOXF2 SNCA TRIP13 VENTX	27 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 TNFAIP3 WBP2
Entrez ID		410	339390
HPRD ID		09617	16721
Ensembl ID		ENSG00000100299	ENSG00000182566
Uniprot IDs		A0A0C4DFZ2 B4DVI5 P15289	B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1
PDB IDs		1AUK 1E1Z 1E2S 1E33 1E3C 1N2K 1N2L 2AIJ 2AIK 2HI8	Not available
GO Terms Enriched among Interactors		None	Extracellular Exosome