ARL1 and COPG2

Number of citations: 0 (PubMedID 10318838)
Data Source: HPRD (in vivo)

		ARL1	COPG2
Name		ARF like GTPase 1	coat protein complex I subunit gamma 2
Structure			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Growth Cone COPI-coated Vesicle Membrane Cytoplasmic Vesicle Bounding Membrane Of Organelle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding Phospholipase D Activator Activity	Structural Molecule Activity
	Biological Process	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Protein Transport Vesicle-mediated Transport Organelle Transport Along Microtubule
Pathways		Retrograde transport at the Trans-Golgi-Network	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Guanosine-5'-Diphosphate	None
GWAS		Lung cancer in never smokers ( 28604730 ) Response to methotrexate in juvenile idiopathic arthritis ( 24709693 )	A body shape index ( 34021172 ) Pancreatic cancer ( 25086665 ) Waist circumference adjusted for body mass index ( 34021172 ) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971 ) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971 )
Interacting Genes		8 interacting genes: ARFIP2 COPG2 DRD2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC	12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10
Entrez ID		400	26958
HPRD ID		04574	05074
Ensembl ID		ENSG00000120805	ENSG00000158623
Uniprot IDs		B4DZG7 P40616	A0A140VK12 Q9UBF2
PDB IDs		1UPT 4DCN 5EE5 5J5C	Not available
GO Terms Enriched among Interactors		Golgi Apparatus Golgi Membrane Trans-Golgi Network Small GTPase Binding Golgi To Plasma Membrane Protein Transport Golgi Vesicle Transport Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Intracellular Protein Localization Membrane Negative Regulation Of Circadian Sleep/wake Cycle, Sleep G Protein-coupled Receptor Complex Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Negative Regulation Of Dopamine Secretion Vesicle-mediated Transport Negative Regulation Of Dopamine Receptor Signaling Pathway Acrosomal Vesicle Cytosol Vesicle-mediated Transport To The Plasma Membrane Protein Transport Establishment Of Protein Localization Post-Golgi Vesicle-mediated Transport Recycling Endosome To Golgi Transport Intracellular Protein Transport Membrane Curvature Sensor Activity Dopamine Binding Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Negative Regulation Of Dephosphorylation Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Branching Morphogenesis Of A Nerve Positive Regulation Of Neurotransmitter Uptake Regulation Of Locomotion Involved In Locomotory Behavior Positive Regulation Of Developmental Growth Late Endosome To Golgi Transport Regulation Of Synapse Structural Plasticity Regulation Of Renal Sodium Excretion Interneuron Migration From The Subpallium To The Cortex Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Establishment Of Localization In Cell	COPI Vesicle Coat COPI-coated Vesicle Membrane Transport Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Vesicle Transport Intra-Golgi Vesicle-mediated Transport Golgi Membrane COPI-coated Vesicle Intracellular Protein Transport Endoplasmic Reticulum Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Establishment Of Localization In Cell Intracellular Protein Localization Cytoplasmic Vesicle Golgi Apparatus Membrane Coat Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Localization Protein Localization To Golgi Apparatus Structural Molecule Activity Cis-Golgi Network MHC Class Ib Protein Complex Assembly Peptide Antigen Stabilization Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Cerebellar Purkinje Cell Layer Maturation Phospholipase D Activator Activity Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs G Protein-coupled Receptor Complex Tapasin-ERp57 Complex Adult Locomotory Behavior Secretory Granule Membrane Conditioned Taste Aversion Sensitization TAP2 Binding TAP Complex Binding Prostaglandin-E Synthase Activity Endoplasmic Reticulum Membrane Habituation Operant Conditioning Unfolded Protein Binding TAP1 Binding