ZKSCAN4 and ZKSCAN7

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		ZKSCAN4	ZKSCAN7
Name		zinc finger with KRAB and SCAN domains 4	zinc finger with KRAB and SCAN domains 7
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway	Generic Transcription Pathway
GWAS		Asthma and major depressive disorder ( 31619474 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Basal metabolic rate ( 31453325 ) Basal metabolic rate variance ( 31453325 ) Brain morphology (MOSTest) ( 32665545 ) Fish- and plant-related diet ( 32066663 ) Hip circumference adjusted for BMI ( 34021172 ) Refractive error ( 32231278 ) Schizophrenia ( 30285260 ) Subcortical volume (MOSTest) ( 32665545 )	No GWAS studies recorded
Interacting Genes		19 interacting genes: CABP5 IL36RN LXN MAP1LC3A MDM4 MEOX2 OGT OSGIN1 PSMA6 TIAM1 TRIM39 ZKSCAN7 ZNF397 ZNF483 ZNF496 ZSCAN20 ZSCAN22 ZSCAN30 ZSCAN32	14 interacting genes: CRK NFIC PGBD1 PLCG2 RHOU SCAND1 TCEANC ZKSCAN4 ZNF446 ZSCAN12 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN32
Entrez ID		387032	55888
HPRD ID		15768	15744
Ensembl ID		ENSG00000187626	ENSG00000196345
Uniprot IDs		A0A0S2Z658 B7Z7H3 Q969J2	A7MAY2 C9J6L6 Q0VAP0 Q9P0L1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Catabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Purine Ribonucleoside Triphosphate Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Primary Metabolic Process Mitophagy Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Response To Yeast DNA Binding Zinc Ion Binding Protein Tyrosine Kinase Binding Phosphotyrosine Residue Binding Sequence-specific Double-stranded DNA Binding Response To Fungus Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Scaffold Protein Binding Response To Cholecystokinin Nucleus Cerebellar Neuron Development Inositol Trisphosphate Biosynthetic Process Establishment Of Cell Polarity