KRT13 and RTL8B

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		KRT13	RTL8B
Name		keratin 13	retrotransposon Gag like 8B
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	None
	Molecular Function	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Regulation Of Translation In Response To Stress Intermediate Filament Organization	None
Pathways		Keratinization Formation of the cornified envelope	None
Diseases		White sponge nevus	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		1 novel interactors: ORMDL3	None recorded
Interacting Genes		70 interacting genes: ABI2 ABI3 AIRIM AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf216 CATSPERT CCHCR1 CCNC CEP57 CEP57L1 CFTR DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 LSM2 MOS MYH1 MYO15B NEFL NEIL3 PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688	11 interacting genes: ALAS1 CCDC102B KRT13 PEG10 RIN3 SDCBP SPG21 TADA2A UBC UBQLN1 UBQLN2
Entrez ID		3860	441518
HPRD ID		01016	19134
Ensembl ID		ENSG00000171401	ENSG00000212747
Uniprot IDs		A1A4E9 P13646	Q17RB0
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Cytosol Structural Constituent Of Cytoskeleton Intermediate Filament Polymerization Or Depolymerization Extracellular Exosome Cytoskeleton Cytoplasm Protein Binding Proteasome Core Complex Epidermis Development Actin-based Cell Projection	Negative Regulation Of Receptor Internalization Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Endocytosis Regulation Of Receptor Internalization Regulation Of Receptor-mediated Endocytosis Positive Regulation Of ERAD Pathway Negative Regulation Of Transport Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Interleukin-5 Receptor Complex Negative Regulation Of Store-operated Calcium Channel Activity Negative Regulation Of Mast Cell Chemotaxis Cytosol Regulation Of Endocytosis 5-aminolevulinate Synthase Activity Response To Nickel Cation Interleukin-5 Receptor Binding Autophagosome Negative Regulation Of G Protein-coupled Receptor Internalization Extracellular Vesicle Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Vesicle-mediated Intercellular Transport Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Response To Platinum Ion Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding Negative Regulation Of Clathrin-dependent Endocytosis Positive Regulation Of Proteasomal Protein Catabolic Process Response To Herbicide Positive Regulation Of Proteolysis Involved In Protein Catabolic Process