KCNC1 and KCNG3

Number of citations: 35 (PubMedID 12060745)
Data Source: HPRD (two hybrid)

		KCNC1	KCNG3
Name		potassium voltage-gated channel subfamily C member 1	potassium voltage-gated channel modifier subfamily G member 3
Structure			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Membrane Axon Dendrite Axolemma Neuron Projection Membrane Dendrite Membrane Neuronal Cell Body Membrane Monoatomic Ion Channel Complex Presynaptic Membrane Cell Projection Neuronal Cell Body Axon Terminus Calyx Of Held Synapse Postsynaptic Membrane	Cytoplasm Endoplasmic Reticulum Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Kinesin Binding Gated Channel Activity Transmembrane Transporter Binding Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Response To Toxic Substance Response To Light Intensity Response To Auditory Stimulus Response To Amine Cerebellum Development Optic Nerve Development Globus Pallidus Development Corpus Callosum Development Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Response To Potassium Ion Protein Homooligomerization Protein Tetramerization Transmembrane Transport Cellular Response To Xenobiotic Stimulus Response To Fibroblast Growth Factor Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Response To Nerve Growth Factor	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dalfampridine	Enflurane Promethazine Miconazole
GWAS		Body mass index ( 26426971 ) Night sleep phenotypes ( 27126917 ) Opioid sensitivity ( 24143882 )	Body mass index ( 25673413 ) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 ) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858 ) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 ) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858 ) Thrombosis ( 26908601 )
Interacting Genes		7 interacting genes: ANK3 KCNG3 KCNH1 KCNV2 LPAR3 TMBIM6 TRARG1	4 interacting genes: KCNB1 KCNB2 KCNC1 KCNF1
Entrez ID		3746	170850
HPRD ID		15936	16232
Ensembl ID		ENSG00000129159	ENSG00000171126
Uniprot IDs		P48547	Q8TAE7
PDB IDs		7PHH 7PHI 7PHK 7PHL 7PQT 7PQU 8F1C 8F1D 8QUC 8QUD	Not available
GO Terms Enriched among Interactors		Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Regulation Of Metal Ion Transport Action Potential Regulation Of Membrane Potential Regulation Of Monoatomic Ion Transport Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Biological Quality Plasma Membrane Inorganic Ion Transmembrane Transport Regulation Of Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Potassium Channel Regulator Activity Regulation Of Monoatomic Ion Transmembrane Transport Establishment Of Protein Localization To Plasma Membrane Monoatomic Ion Transport Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cation Transmembrane Transport Axon Negative Regulation Of Monoatomic Ion Transmembrane Transport Cyclic Nucleotide Binding Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Potassium Ion Transport Negative Regulation Of Monoatomic Ion Transport Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Maintenance Of Protein Location In Plasma Membrane Endoribonuclease Inhibitor Activity Negative Regulation Of Transmembrane Transport Positive Regulation Of Cell Communication By Electrical Coupling Vesicle-mediated Transport To The Plasma Membrane Membrane Lysophosphatidic Acid Receptor Activity Regulation Of Transport Cellular Response To Metal Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Negative Regulation Of Calcium Ion Transport Into Cytosol Cellular Response To Magnesium Ion Positive Regulation Of Monoatomic Ion Transport Negative Regulation Of IRE1-mediated Unfolded Protein Response Glucose Import In Response To Insulin Stimulus Protein Localization To Plasma Membrane	Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Action Potential Delayed Rectifier Potassium Channel Activity Monoatomic Ion Channel Complex Neuronal Cell Body Membrane Potassium Ion Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Protein Homooligomerization Potassium Channel Regulator Activity Protein Complex Oligomerization Regulation Of Membrane Potential Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Inorganic Ion Transmembrane Transport Dendrite Membrane Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Monoatomic Ion Transport Non-motile Cilium Assembly Neuronal Cell Body Transmembrane Transport Cellular Component Assembly Dendrite Cell Projection Protein-containing Complex Assembly Regulation Of Potassium Ion Transport Localization Within Membrane Protein-containing Complex Organization Transmembrane Transporter Binding Perikaryon Regulation Of Transport Positive Regulation Of Norepinephrine Secretion Globus Pallidus Development Gated Channel Activity Neuron Projection Membrane Regulation Of Centriole-centriole Cohesion Clustering Of Voltage-gated Potassium Channels Intracellular Protein Localization Protein Localization To Plasma Membrane Positive Regulation Of Long-term Synaptic Depression Positive Regulation Of Protein Localization To Centrosome Protein Localization To Cell Periphery Postsynaptic Membrane Proximal Dendrite Cholesterol Catabolic Process Cilium Assembly