ANXA11 and ENO2

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		ANXA11	ENO2
Name		annexin A11	enolase 2
Structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Spindle Cytosol Cytoskeleton Plasma Membrane Vesicle Membrane Membrane Midbody Extracellular Matrix Melanosome Specific Granule Azurophil Granule Phagocytic Vesicle Extracellular Exosome	Phosphopyruvate Hydratase Complex Photoreceptor Inner Segment Extracellular Space Cytoplasm Cytosol Plasma Membrane Cell Cortex Cell Surface Membrane Growth Cone Neuronal Cell Body Perikaryon Membrane Raft Extracellular Exosome Synaptic Membrane
	Molecular Function	Phosphatidylserine Binding RNA Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylethanolamine Binding MHC Class II Protein Complex Binding S100 Protein Binding Calcium-dependent Protein Binding	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Protein Binding Lyase Activity Enzyme Binding Identical Protein Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Phagocytosis Cytokinetic Process Cell Division Response To Calcium Ion	Gluconeogenesis Glycolytic Process Response To Xenobiotic Stimulus Response To Estradiol Canonical Glycolysis
Pathways		None	Glycolysis Gluconeogenesis
Drugs		None	2-Phosphoglycolic Acid
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326 ) Diabetic kidney disease ( 26305897 ) Sarcoidosis ( 22936702 32826979 ) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848 )	No GWAS studies recorded
Interacting Genes		19 interacting genes: ALG2 ARSA CDC42 CEP55 ENO2 EWSR1 FUBP1 HNRNPH3 KRTAP13-2 KRTAP6-2 NFKBID OGT PDCD6 PLSCR1 S100A6 SRI TFG WWOX ZDHHC17	27 interacting genes: A2M ACD AKT1 ANXA11 BMERB1 C6orf47 ENSA EXOC5 HABP4 HK1 HSF1 IL17B MAP4 MTNR1A NAT9 NDUFS7 POT1 SIGIRR SNUPN ST3GAL2 SUMO4 TERF1 TINF2 TUBA4A UBE2C UBE3A USP2-AS1
Entrez ID		311	2026
HPRD ID		03983	00573
Ensembl ID		ENSG00000122359	ENSG00000111674
Uniprot IDs		P50995 Q5T0G8	P09104 Q6FHV6
PDB IDs		9FOF 9FOR	1TE6 2AKM 2AKZ 3UCC 3UCD 3UJE 3UJF 3UJR 3UJS 4ZA0 4ZCW 5EU9 5IDZ 5TD9 5TIJ 7MBH
GO Terms Enriched among Interactors		Identical Protein Binding	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Telomere Maintenance Via Telomerase Translation Elongation Factor Binding Negative Regulation Of Chromosome Organization RNA-templated DNA Biosynthetic Process Negative Regulation Of Cellular Component Organization Regulation Of DNA Biosynthetic Process Positive Regulation Of Organelle Organization Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Positive Regulation Of Chromosome Organization Maintenance Of Protein Location In Mitochondrion Regulation Of Telomere Maintenance Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Chromosome Organization Regulation Of Establishment Of Protein Localization To Chromosome Telomere Organization Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Regulation Of Organelle Organization Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Regulation Of DNA Metabolic Process Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region Chromosome, Telomeric Region Establishment Of Protein Localization To Organelle Organelle Organization DNA Biosynthetic Process Anaphase-promoting Complex-dependent Catabolic Process Negative Regulation Of Cilium Assembly Cell Division Microtubule Cytoskeleton Ubiquitin-like Protein Ligase Binding Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Mitotic Cell Cycle Regulation Of TRNA Methylation