FOXR1 and PPCDC

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid, two hybrid)

		FOXR1	PPCDC
Name		forkhead box R1	phosphopantothenoylcysteine decarboxylase
Structure		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Cytosol Phosphopantothenoylcysteine Decarboxylase Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Catalytic Activity Phosphopantothenoylcysteine Decarboxylase Activity Protein Binding FMN Binding Lyase Activity Carboxy-lyase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Brain Development Positive Regulation Of Transcription By RNA Polymerase II	Coenzyme A Biosynthetic Process
Pathways		None	Coenzyme A biosynthesis
Drugs		None	Flavin mononucleotide Pantothenoylaminoethenethiol
GWAS		Asthma ( 31959851 )	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054 ) Apolipoprotein A1 levels ( 32203549 ) Blood trace element (Zn levels) ( 23720494 ) Caffeine consumption ( 21490707 ) Coffee consumption (cups per day) ( 31837886 ) Heel bone mineral density ( 30598549 ) Lymphocyte count ( 32888494 ) Mean corpuscular hemoglobin concentration ( 32888494 ) Mean reticulocyte volume ( 32888494 ) Multisite chronic pain ( 33830993 ) Neutrophil count ( 32888494 ) Platelet count ( 32888494 ) Reticulocyte fraction of red cells ( 32888494 ) Systemic lupus erythematosus ( 26502338 ) White blood cell count ( 32888494 )
Interacting Genes		6 interacting genes: BANP CEP19 DPPA4 GMCL1 MEOX2 PPCDC	13 interacting genes: CENPT DBI DDIT4L FOXR1 NAA80 NTAQ1 PLEKHF2 PPIG PSMA1 SREK1IP1 TXN2 UBE2I ZNF232
Entrez ID		283150	60490
HPRD ID		13551	14377
Ensembl ID		ENSG00000176302	ENSG00000138621
Uniprot IDs		B0YJ16 Q6PIV2	H3BQB0 H3BRQ0 H3BSE3 H3BU63 Q96CD2
PDB IDs		Not available	1QZU
GO Terms Enriched among Interactors		Phosphopantothenoylcysteine Decarboxylase Activity Phosphopantothenoylcysteine Decarboxylase Complex Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	None