GOLGB1 and VTI1B

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		GOLGB1	VTI1B
Name		golgin B1	vesicle transport through interaction with t-SNAREs 1B
Structure		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Cytosol Membrane	Extracellular Region Cytoplasm Lysosome Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Synaptic Vesicle Endomembrane System ER To Golgi Transport Vesicle Membrane Membrane Platelet Alpha Granule Lumen SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Neuronal Cell Body Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Presynaptic Endosome Membrane
	Molecular Function	RNA Binding Protein Binding Sequence-specific DNA Binding	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity
	Biological Process	Regulation Of DNA-templated Transcription Golgi Organization Protein Localization To Pericentriolar Material	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Macroautophagy Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane
Pathways		Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Platelet degranulation
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Mean reticulocyte volume ( 32888494 )	Blood protein levels ( 30072576 )
Interacting Genes		19 interacting genes: ACBD3 ADRB2 BRMS1 CAV2 CEP126 ECPAS ITSN2 MAPK7 NDUFA1 NOD2 PFN2 RNF10 SKIL SLC2A3 SREBF2 UBE2I USO1 USP7 VTI1B	38 interacting genes: AQP6 ASGR2 BIK CD46 CD79A CFTR CRB3 CREB3 ERGIC3 FCGR1A GOLGB1 GPR35 GPX8 JAGN1 KASH5 KLRC1 KRTAP10-7 LDLRAD1 LMNA MANBAL PTPN5 REEP4 RNASEK SAR1A SLC16A7 SLC18A1 SLC35H1 STX1A STX2 STX4 STX7 STX8 SYNE4 TMEM14B TMEM234 TMEM51 TNK2 TRIM59
Entrez ID		2804	10490
HPRD ID		03933	04440
Ensembl ID		ENSG00000173230	ENSG00000100568
Uniprot IDs		A0A8J9C4H3 E7EU81 Q14789	Q9UEU0
PDB IDs		Not available	2V8S
GO Terms Enriched among Interactors		PML Body Vesicle Docking ER To Golgi Transport Vesicle Membrane Vesicle Fusion With Golgi Apparatus Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Cellular Response To Laminar Fluid Shear Stress Organelle Membrane Fusion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Laminar Fluid Shear Stress Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Temperature Homeostasis Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of RNA Metabolic Process Positive Regulation Of Autophagy Receptor-mediated Endocytosis Regulation Of Autophagy Positive Regulation Of Mini Excitatory Postsynaptic Potential Golgi Apparatus Cytoplasm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Organelle Fusion Membrane Fusion Cellular Response To Fluid Shear Stress Response To Fluid Shear Stress SUMO Conjugating Enzyme Activity Golgi Vesicle Docking Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Mitophagy	Membrane Chloride Channel Inhibitor Activity Vesicle Docking Organelle Localization By Membrane Tethering SNAP Receptor Activity Membrane Docking SNARE Complex SNARE Binding Vesicle-mediated Transport Endomembrane System Vesicle Fusion Organelle Membrane Fusion Organelle Localization Membrane Organization Organelle Fusion Membrane Fusion Vesicle Organization Cornified Envelope Assembly Intracellular Protein Transport Meiotic Nuclear Membrane Microtubule Tethering Complex Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Membrane Assembly Positive Regulation Of Immune Effector Process SNARE Complex Assembly Endoplasmic Reticulum Membrane Regulation Of Insulin Secretion Regulation Of Protein Localization Regulation Of Peptide Hormone Secretion Regulation Of Cellular Localization Positive Regulation Of Exocytosis Exocytosis Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Lymphocyte Mediated Immunity Nuclear Envelope Organization Protein Binding Water Transport Endoplasmic Reticulum Regulation Of Adaptive Immune Response Neurotransmitter Transport Schaffer Collateral - CA1 Synapse Establishment Of Localization In Cell Nitrate Transmembrane Transporter Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Basolateral Plasma Membrane Protein Transport Presynaptic Active Zone Membrane High-affinity IgG Receptor Activity Inhibitory MHC Class Ib Receptor Activity