GFER and BNIPL

Number of citations: 0 (PubMedID 12681488)
Data Source: HPRD (two hybrid, in vitro, in vivo)

		GFER	BNIPL
Name		growth factor, augmenter of liver regeneration	BCL2 interacting protein like
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Cytosol	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Growth Factor Activity Protein-disulfide Reductase Activity Oxidoreductase Activity Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity Flavin Adenine Dinucleotide Binding	Protein Binding Identical Protein Binding
	Biological Process	Liver Development Signal Transduction Mitochondrial Disulfide Relay System	Apoptotic Process Negative Regulation Of Cell Population Proliferation Regulation Of Growth Rate
Pathways		Mitochondrial protein import	None
Drugs		Flavin adenine dinucleotide	None
GWAS		No GWAS studies recorded	Body mass index ( 26426971 ) Chronic kidney disease ( 20383146 ) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429 ) Type 2 diabetes ( 30297969 )
Interacting Genes		8 interacting genes: ASCC2 BNIPL COPS2 COPS5 PLEKHF2 SMAD2 TXN YY1	13 interacting genes: ARHGAP1 BCL2 BCL2L1 BNIP2 FKBP8 GFER MIF NME2 PXDN PYCR1 RECQL5 RHOU SNAPIN
Entrez ID		2671	149428
HPRD ID		02954	16557
Ensembl ID		ENSG00000127554	ENSG00000163141
Uniprot IDs		P55789	Q7Z465
PDB IDs		3MBG 3O55 3TK0 3U2L 3U2M 3U5S 4LDK	Not available
GO Terms Enriched among Interactors		Protein Deneddylation Protein Neddylation Regulation Of Protein Neddylation COP9 Signalosome SMAD Binding Oxidoreductase Activity, Acting On Metal Ions, NAD Or NADP As Acceptor [methionine Synthase] Reductase (NADPH) Activity Protein-L-histidine N-pros-methyltransferase Activity	Dendritic Cell Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Programmed Cell Death Regulation Of Intrinsic Apoptotic Signaling Pathway BH3 Domain Binding Negative Regulation Of Leukocyte Apoptotic Process Regulation Of Cell Communication Regulation Of Signaling Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of B Cell Apoptotic Process Protein Homotrimerization Regulation Of Signal Transduction Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Protein Trimerization Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Anoikis Regulation Of B Cell Apoptotic Process Cytosol Negative Regulation Of Myeloid Cell Apoptotic Process Identical Protein Binding Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Apoptotic Signaling Pathway Isomerase Activity Regulation Of Anoikis Positive Regulation Of Mononuclear Cell Proliferation Regulation Of Intracellular Signal Transduction Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Leukocyte Proliferation Sensory Organ Development Regulation Of Myeloid Cell Apoptotic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Lymphocyte Apoptotic Process Cellular Response To Alkaloid Pigment Granule Organization Channel Activity Regulation Of Cellular Localization Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand