AK5 and STRN4

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		AK5	STRN4
Name		adenylate kinase 5	striatin 4
Structure			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Centriolar Satellite	Cytoplasm Dendrite Protein-containing Complex Neuronal Cell Body Dendritic Spine FAR/SIN/STRIPAK Complex Postsynapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Nucleotide Binding AMP Kinase Activity Nucleoside Diphosphate Kinase Activity ATP Binding Kinase Activity Transferase Activity Nucleobase-containing Compound Kinase Activity	Protein Binding Calmodulin Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process ADP Biosynthetic Process DADP Biosynthetic Process Pyrimidine Ribonucleotide Biosynthetic Process ATP Metabolic Process Nucleoside Monophosphate Phosphorylation	Negative Regulation Of Hippo Signaling Regulation Of Modification Of Postsynaptic Structure
Pathways		Interconversion of nucleotide di- and triphosphates	None
GWAS		Body mass index ( 25673413 ) Chronotype ( 26955885 27494321 30696823 ) Eosinophil percentage of white cells ( 27863252 ) Estimated glomerular filtration rate ( 31152163 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Household income (MTAG) ( 31844048 ) Immature fraction of reticulocytes ( 32888494 ) Lung adenocarcinoma ( 28604730 ) Lung cancer ( 28604730 ) Lung cancer in ever smokers ( 28604730 ) Mean reticulocyte volume ( 32888494 ) Morning person ( 30696823 ) Morning vs. evening chronotype ( 27494321 26955885 26835600 ) Sleep traits (multi-trait analysis) ( 27992416 ) Type 2 diabetes (age of onset) ( 28060188 ) Urinary albumin excretion ( 30220432 ) Urinary albumin-to-creatinine ratio ( 31630189 )	Aspartate aminotransferase levels ( 33547301 ) Chronic lymphocytic leukemia ( 18758461 28165464 ) Primary sclerosing cholangitis ( 23603763 )
Interacting Genes		7 interacting genes: CPNE6 INTS15 NUCKS1 RNF114 STRN4 TRIM46 UGDH	28 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 TNIK WIPI2 WNT7A
Entrez ID		26289	29888
HPRD ID		10472	18125
Ensembl ID		ENSG00000154027	ENSG00000090372
Uniprot IDs		Q9Y6K8	F5GYK2 Q59GV6 Q9NRL3
PDB IDs		2BWJ	Not available
GO Terms Enriched among Interactors		UDP-glucuronate Biosynthetic Process UDP-glucose 6-dehydrogenase Activity Gene Conversion Positive Regulation Of Anterograde Dense Core Granule Transport UDP-glucuronate Metabolic Process Proximal Neuron Projection	MAP Kinase Kinase Kinase Kinase Activity MAPK Cascade Regulation Of MAPK Cascade JNK Cascade Regulation Of JNK Cascade Intracellular Signaling Cassette Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Kinase Activity Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Transforming Growth Factor Beta Stimulus Nucleotide Binding ATP Binding Response To Transforming Growth Factor Beta Protein Serine Kinase Activity Protein Phosphorylation Signal Transduction Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Phosphorylation Cytokine Activity Regulation Of Fibroblast Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Junction Assembly Regulation Of Intracellular Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential